Unit of Translational Medicine, Department of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
Joint Bone Spine. 2013 Oct;80(5):523-4. doi: 10.1016/j.jbspin.2013.01.011. Epub 2013 Aug 9.
We report two rare cases of adult-onset phalangeal microgeodic syndrome (PMS), which commonly develops in children. Both cases were Japanese women, with case 1: 60 years old and case 2: 58 years old. They developed swelling and stiffness in their fingers in winter, and their symptoms disappeared without any treatment in summer. Magnetic resonance imaging (MRI) of bilateral hands showed diffuse bone edema of the middle and proximal phalanges in winter, but the abnormal findings also disappeared in summer. The specific abnormalities observed on MRI were very useful for the diagnosis of PMS. Interestingly, they appeared in winter and disappeared in summer in parallel with the symptoms.
我们报告了两例罕见的成人指骨微骨瘤综合征(PMS)病例,该病常见于儿童。两例患者均为日本女性,病例 1 为 60 岁,病例 2 为 58 岁。她们在冬季出现手指肿胀和僵硬,夏季无需治疗症状即可自行消失。双手磁共振成像(MRI)显示冬季双侧中近端指骨弥漫性骨水肿,但夏季异常发现也消失了。MRI 观察到的具体异常对 PMS 的诊断非常有用。有趣的是,它们与症状平行,冬季出现,夏季消失。