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2004年至2010年期间，希腊北部10岁以下儿童流感病毒的实验室监测。

Laboratory surveillance of influenza virus in children under 10 years old, in northern Greece, during 2004-2010.

作者信息

Gioula G, Melidou A, Exindari M, Chatzopoulou E, Chatzidimitriou D, Malisiovas N

机构信息

National Influenza Centre, Microbiology Department, Faculty of Medicine, Aristotle University of Thessaloniki, Greece.

出版信息

Hippokratia. 2013 Jan;17(1):17-9.

PMID:23935338
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3738271/
Abstract

OBJECTIVES

Influenza viruses constitute one of the most common pathogens that cause acute respiratory disease in children. The aim of this study is to present the contribution of influenza viruses to influenza-like illness (ILI) in children (aged<10 years old) in Northern Greece during six influenza seasons (2004-2010).

MATERIALS AND METHODS

1,242 pharyngeal swabs or/and washes from children younger than 10 years old, presented as ILI infections during the last six influenza seasons (2004-2005, 2005-2006, 2006-2007, 2007-2008, 2008-2009 and 2009-2010) were examined for influenza A and B by Real-time one step RT-PCR.

RESULTS

Influenza viruses were detected in 431 (34.7%) of the 1,242 specimens. In a total of 372 specimens were positive for influenza A and 58 for influenza B. The majority of the infected young patients were 6-10 years old (51.9%).

CONCLUSION

Our results show that in N. Greece, influenza viruses type A and B contribute to ILI presenting infections at a rate of 34.7 % in children younger than 10 years old.

摘要

目的

流感病毒是导致儿童急性呼吸道疾病的最常见病原体之一。本研究的目的是呈现流感病毒在六个流感季节（2004 - 2010年）期间对希腊北部10岁以下儿童流感样疾病（ILI）的影响。

材料与方法

对1242份来自10岁以下儿童的咽拭子或/和冲洗液进行检测，这些样本是在过去六个流感季节（2004 - 2005年、2005 - 2006年、2006 - 2007年、2007 - 2008年、2008 - 2009年和2009 - 2010年）期间作为ILI感染病例送来的，采用实时一步法逆转录聚合酶链反应（Real-time one step RT-PCR）检测甲型和乙型流感病毒。

结果

在1242份样本中，431份（34.7%）检测到流感病毒。其中，甲型流感病毒阳性的样本有372份，乙型流感病毒阳性的样本有58份。大多数受感染的年轻患者年龄在6 - 10岁之间（51.9%）。

结论

我们的结果表明，在希腊北部，甲型和乙型流感病毒导致10岁以下儿童ILI感染的比例为34.7%。