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多发性硬化症患者大剂量使用类固醇后发生脑静脉血栓形成:一例报告

Cerebral venous thrombosis after high dose steroid in multiple sclerosis: a case report.

作者信息

Gazioglu S, Solmaz D, Boz C

机构信息

Department of Neurology, Karadeniz Technical University Medical Faculty, Trabzon, Turkey.

出版信息

Hippokratia. 2013 Jan;17(1):88-90.

Abstract

Cerebral venous thrombosis (CVT) is a clinical condition which is caused by the partial or complete occlusion of the dural sinuses and cerebral veins. Cases of associated CVT and multiple sclerosis (MS) have been reported and CVT development has been attributed to the previous lumbar puncture (LP) in majority of these cases. We report a case of 32-year-old woman with no previous history of recent LP, who developed CVT after high dose intravenous methylprednisolone and discuss the possible role of high dose steroids in development of CVT in MS patients.

摘要

脑静脉血栓形成(CVT)是一种由硬脑膜窦和脑静脉部分或完全闭塞引起的临床病症。已有CVT与多发性硬化症(MS)相关的病例报道,在大多数此类病例中,CVT的发生归因于先前的腰椎穿刺(LP)。我们报告一例32岁女性,既往无近期LP史,在接受大剂量静脉注射甲基强的松龙后发生CVT,并讨论大剂量类固醇在MS患者CVT发生中的可能作用。

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