• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

环孢素A诱导的颅内血栓形成并发症：系统评价与病例报告

Cyclosporine-A-Induced Intracranial Thrombotic Complications: Systematic Review and Cases Report.

作者信息

Song Si-Ying, Wang Zhong-Ao, Ding Yu-Chuan, Ji Xun-Ming, Meng Ran

机构信息

Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, China.

Advanced Center of Stroke, Beijing Institute for Brain Disorders, Beijing, China.

出版信息

Front Neurol. 2021 Feb 11;11:563037. doi: 10.3389/fneur.2020.563037. eCollection 2020.

DOI:10.3389/fneur.2020.563037
PMID:33643175
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7906016/
Abstract

This study reported two cases of intracranial thrombotic events of aplastic anemia (AA) under therapy with cyclosporine-A (CsA) and reviewed both drug-induced cerebral venous thrombosis (CVT) and CsA-related thrombotic events systematically. We searched PubMed Central (PMC) and EMBASE up to Sep 2019 for publications on drug-induced CVT and Cs-A-induced thrombotic events. Medical subject headings and Emtree headings were used with the following keywords: "cyclosporine-A" and "cerebral venous thrombosis OR cerebral vein thrombosis" and "stroke OR Brain Ischemia OR Brain Infarction OR cerebral infarction OR intracerebral hemorrhage OR intracranial hemorrhage." We found that CsA might be a significant risk factor in inducing not only CVT but also cerebral arterial thrombosis in patients with AA.

摘要

本研究报告了2例在接受环孢素A（CsA）治疗的再生障碍性贫血（AA）患者中发生的颅内血栓形成事件，并系统回顾了药物性脑静脉血栓形成（CVT）和与CsA相关的血栓形成事件。我们检索了截至2019年9月的PubMed Central（PMC）和EMBASE，以查找有关药物性CVT和CsA诱导的血栓形成事件的出版物。医学主题词和Emtree主题词与以下关键词一起使用：“环孢素A”、“脑静脉血栓形成或脑静脉血栓”、“中风或脑缺血或脑梗死或脑梗塞或脑出血或颅内出血”。我们发现，CsA可能是诱导AA患者不仅发生CVT而且发生脑动脉血栓形成的重要危险因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e07/7906016/21c5d941a313/fneur-11-563037-g0007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e07/7906016/6f818a48a9ca/fneur-11-563037-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e07/7906016/fd2804327570/fneur-11-563037-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e07/7906016/b50960817133/fneur-11-563037-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e07/7906016/3cc1030a2e59/fneur-11-563037-g0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e07/7906016/8c38e5342bb7/fneur-11-563037-g0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e07/7906016/72dbf19e15d2/fneur-11-563037-g0006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e07/7906016/21c5d941a313/fneur-11-563037-g0007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e07/7906016/6f818a48a9ca/fneur-11-563037-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e07/7906016/fd2804327570/fneur-11-563037-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e07/7906016/b50960817133/fneur-11-563037-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e07/7906016/3cc1030a2e59/fneur-11-563037-g0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e07/7906016/8c38e5342bb7/fneur-11-563037-g0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e07/7906016/72dbf19e15d2/fneur-11-563037-g0006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e07/7906016/21c5d941a313/fneur-11-563037-g0007.jpg

相似文献

1
Cyclosporine-A-Induced Intracranial Thrombotic Complications: Systematic Review and Cases Report.环孢素A诱导的颅内血栓形成并发症：系统评价与病例报告
Front Neurol. 2021 Feb 11;11:563037. doi: 10.3389/fneur.2020.563037. eCollection 2020.
2
Cerebral Venous Thrombosis in Patients With Heparin-Induced Thrombocytopenia a Systematic Review.肝素诱导的血小板减少症患者的脑静脉血栓形成：系统评价。
Stroke. 2022 Jun;53(6):1892-1903. doi: 10.1161/STROKEAHA.121.036824. Epub 2022 Mar 4.
3
Risk factors governing the development of cerebral vein and dural sinus thrombosis after craniotomy in patients with intracranial tumors.颅内肿瘤患者开颅术后颅内静脉窦及硬脑膜窦血栓形成的危险因素。
J Neurosurg. 2018 Feb;128(2):373-379. doi: 10.3171/2016.11.JNS161871. Epub 2017 Apr 7.
4
Ischemic Stroke and Vaccine-Induced Immune Thrombotic Thrombocytopenia following COVID-19 Vaccine: A Case Report with Systematic Review of the Literature.COVID-19 疫苗接种后缺血性脑卒中与疫苗诱导的免疫性血栓性血小板减少症：病例报告并文献系统回顾。
Cerebrovasc Dis. 2022;51(6):722-734. doi: 10.1159/000524290. Epub 2022 May 5.
5
Outcomes of Cerebral Venous Thrombosis due to Vaccine-Induced Immune Thrombotic Thrombocytopenia After the Acute Phase.疫苗诱导免疫性血栓性血小板减少症后急性期的脑静脉血栓形成的结局。
Stroke. 2022 Oct;53(10):3206-3210. doi: 10.1161/STROKEAHA.122.039575. Epub 2022 Sep 9.
6
Cerebral venous thrombosis and severe acute respiratory syndrome coronavirus-2 infection: A systematic review and meta-analysis.脑静脉血栓形成与严重急性呼吸综合征冠状病毒 2 感染：系统评价和荟萃分析。
Eur J Neurol. 2021 Oct;28(10):3478-3490. doi: 10.1111/ene.14727. Epub 2021 Feb 2.
7
Pediatric Cortical Vein Thrombosis: Frequency and Association With Venous Infarction.小儿皮质静脉血栓形成：发生率及其与静脉梗死的关联
Stroke. 2016 Mar;47(3):866-8. doi: 10.1161/STROKEAHA.115.011291.
8
Systemic thrombolysis for cerebral venous and dural sinus thrombosis: a systematic review.用于脑静脉和硬脑膜窦血栓形成的全身溶栓治疗：一项系统评价
Cerebrovasc Dis. 2014;37(1):43-50. doi: 10.1159/000356840. Epub 2013 Dec 18.
9
Apixaban for the Treatment of Cerebral Venous Sinus Thrombosis: A Single-Centre Experience and Systematic Review of the Literature.阿哌沙班治疗颅内静脉窦血栓形成：单中心经验和文献系统评价。
CNS Drugs. 2023 Feb;37(2):133-141. doi: 10.1007/s40263-022-00981-7. Epub 2023 Jan 17.
10
Safety of Pregnancy After Cerebral Venous Thrombosis: A Systematic Review.脑静脉血栓形成后妊娠的安全性：一项系统评价。
Stroke. 2016 Mar;47(3):713-8. doi: 10.1161/STROKEAHA.115.011955. Epub 2016 Jan 21.

引用本文的文献

1
Prevalence and incidence of comorbidities in patients with atopic dermatitis, psoriasis, alopecia areata, and vitiligo using a Japanese claims database.利用日本索赔数据库分析特应性皮炎、银屑病、斑秃和白癜风患者共病的患病率和发病率。
J Dermatol. 2025 May;52(5):841-854. doi: 10.1111/1346-8138.17643. Epub 2025 Feb 7.
2
Balloon-Assisted Thrombectomy and Intrasinus Urokinase Thrombolysis for Severe Cerebral Venous Sinus Thrombosis.球囊辅助血栓切除术及窦内尿激酶溶栓治疗严重脑静脉窦血栓形成
Front Neurol. 2021 Nov 18;12:735540. doi: 10.3389/fneur.2021.735540. eCollection 2021.
3
Nonthrombotic internal jugular venous stenosis may facilitate cerebral venous thrombosis.

本文引用的文献

1
A case report of oral contraceptive misuse induced cerebral venous sinus thrombosis and dural arteriovenous fistula.一例口服避孕药滥用致脑静脉窦血栓形成及硬脑膜动静脉瘘的病例报告
Medicine (Baltimore). 2019 Aug;98(33):e16440. doi: 10.1097/MD.0000000000016440.
2
Dulaglutide-induced cerebral venous thrombosis in a patient with type 2 diabetes mellitus.度拉糖肽诱发2型糖尿病患者脑静脉血栓形成。
BMJ Case Rep. 2018 Nov 8;2018:bcr-2018-226346. doi: 10.1136/bcr-2018-226346.
3
Association of Anemia with Stroke Severity in Acute Ischemic Stroke Patients.
非血栓性颈内静脉狭窄可能促进脑静脉血栓形成。
CNS Neurosci Ther. 2021 Nov;27(11):1396-1408. doi: 10.1111/cns.13719. Epub 2021 Aug 16.
急性缺血性卒中患者贫血与卒中严重程度的关联
Cureus. 2018 Jun 23;10(6):e2870. doi: 10.7759/cureus.2870.
4
Cyclosporin A-related cerebral venous sinus thrombosis: A case report.环孢素A相关的脑静脉窦血栓形成：一例报告。
Medicine (Baltimore). 2018 Aug;97(31):e11642. doi: 10.1097/MD.0000000000011642.
5
Cerebral venous thrombosis requiring invasive treatment for elevated intracranial pressure in women with combined hormonal contraceptive intake: risk factors, anatomical distribution, and clinical presentation.合并激素避孕药物使用的女性因颅内压升高而需要侵入性治疗的脑静脉血栓形成：危险因素、解剖分布和临床表现。
Neurosurg Focus. 2018 Jul;45(1):E12. doi: 10.3171/2018.4.FOCUS1891.
6
Superior Sagittal Sinus Thrombosis Related to the Use of Tamoxifen: A Case Report and Review of Literature.
Conn Med. 2016 Sep;80(8):487-489.
7
Norethisterone enanthate-induced cerebral venous sinus thrombosis (CVST).庚酸炔诺酮诱发的大脑静脉窦血栓形成（CVST）。
BMJ Case Rep. 2017 Nov 14;2017:bcr-2017-222418. doi: 10.1136/bcr-2017-222418.
8
Cerebral Venous Sinus Thrombosis Due to Low-molecular-weight Heparin-induced Thrombocytopenia.低分子肝素诱导的血小板减少症所致脑静脉窦血栓形成
Neurologist. 2017 Nov;22(6):241-244. doi: 10.1097/NRL.0000000000000146.
9
The Development of Cerebral Venous Thrombosis after Tadalafil Ingestion in a Patient with Antiphospholipid Syndrome.一名抗磷脂综合征患者服用他达拉非后发生脑静脉血栓形成
Intern Med. 2017;56(10):1235-1237. doi: 10.2169/internalmedicine.56.7864. Epub 2017 May 15.
10
Isolated Cortical Venous Thrombosis as a Mimic for Cortical Subarachnoid Hemorrhage.孤立性皮质静脉血栓形成误诊为皮质下蛛网膜下腔出血
World Neurosurg. 2016 May;89:727.e5-7. doi: 10.1016/j.wneu.2016.01.009. Epub 2016 Jan 21.