Tannen R L, Falls W F, Brackett N C
Nephron. 1975;15(2):111-23. doi: 10.1159/000180502.
17 patients with recurrent calcium-containing renal calculi were studied using the short NH4Cl test and one subject with 'incomplete renal tubular acidosis' was identified. In retrospect the only clue to this diagnosis was a fasting, morning urine pH exceeding 6.0 units. Fasting morning urine pH, which is usually less than 6.0 in subjects who acidify normally, is proposed as a simple screening test for 'incomplete RTA'. Modified high dose NH4Cl tests and Na2SO4 tests were performed in this subject and other patients with either complete or incomplete distal renal tubular acidosis. These studies suggest that the ability to lower urine pH is impaired less with the incomplete than with the complete form of the disease.
对17例复发性含钙肾结石患者进行了短程氯化铵试验研究，确定了1例患有“不完全肾小管酸中毒”的患者。回顾来看，该诊断的唯一线索是空腹晨尿pH值超过6.0单位。空腹晨尿pH值在正常酸化的受试者中通常小于6.0，现提议将其作为“不完全肾小管酸中毒”的一项简单筛查试验。对该患者以及其他患有完全性或不完全性远端肾小管酸中毒的患者进行了改良大剂量氯化铵试验和硫酸钠试验。这些研究表明，与疾病的完全形式相比，不完全形式的疾病降低尿液pH值的能力受损程度较小。
