Kong Fei, Cai Bai-Zhen, Chen Xian-Zhao, Zhang Jian, Wang Yi-Ming
Department of Radiotherapy, The People's Hospital of Hainan Province, Haikou, Hainan 570311, P.R. China.
Exp Ther Med. 2013 Jul;6(1):57-60. doi: 10.3892/etm.2013.1100. Epub 2013 May 8.
This study aimed to investigate the risk factors influencing the prognosis of patients receiving conventional fractionation radiotherapy. A retrospective analysis of clinical data from 100 patients with nasopharyngeal carcinoma receiving radiotherapy was conducted. The Chi-square test was used to screen the relevant factors and Cox multiple-factor analysis was used to investigate the risk factors influencing the survival of patients. One-factor analysis results revealed that tumor stage, tumor diameter, prescription dose completion and radiotherapy regularity are related to the prognosis of nasopharyngeal carcinoma and multiple-factor analysis results revealed that tumor stage, radiotherapy dose and radiotherapy regularity are independent risk factors influencing prognosis. The prognosis of patients with nasopharyngeal carcinoma receiving radiotherapy is related to tumor progression and an adequate dose of regular radiotherapy improves the prognosis of patients.
本研究旨在探讨影响接受常规分割放疗患者预后的危险因素。对100例接受放疗的鼻咽癌患者的临床资料进行回顾性分析。采用卡方检验筛选相关因素，采用Cox多因素分析探讨影响患者生存的危险因素。单因素分析结果显示，肿瘤分期、肿瘤直径、处方剂量完成情况及放疗规律性与鼻咽癌预后相关，多因素分析结果显示，肿瘤分期、放疗剂量及放疗规律性是影响预后的独立危险因素。接受放疗的鼻咽癌患者的预后与肿瘤进展相关，足量规律放疗可改善患者预后。
