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血管免疫母细胞性T细胞淋巴瘤相关的纯红细胞再生障碍伴腹痛

Angioimmunoblastic T-cell lymphoma-associated pure red cell aplasia with abdominal pain.

作者信息

Tao Jin, Zheng Feng-Ping, Tian Hong, Lin Ying, Li Jian-Zhong, Chen Xiao-Liang, Chen Jian-Ning, Shao Chun-Kui, Wu Bin

机构信息

Jin Tao, Feng-Ping Zheng, Hong Tian, Ying Lin, Jian-Zhong Li, Xiao-Liang Chen, Bin Wu, Department of Gastroenterology, The Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou 510630, Guangdong Province, China.

出版信息

World J Clin Oncol. 2013 Aug 10;4(3):75-80. doi: 10.5306/wjco.v4.i3.75.

Abstract

Angioimmunoblastic T-cell lymphoma (AITL) is a unique type of peripheral T-cell lymphoma with a constellation of clinical symptoms and signs, including weight loss, fever, chills, anemia, skin rash, hepatosplenomegaly, lymphadenopathy, thrombocytopenia and polyclonal hypergammaglobulinemia. The histological features of AITL are also distinctive. Pure red cell aplasia is a bone marrow failure characterized by progressive normocytic anemia and reticulocytopenia without leucopenia or thrombocytopenia. However, AITL with abdominal pain and pure red cell aplasia has rarely been reported. Here, we report a rare case of AITL-associated pure red cell aplasia with abdominal pain. The diagnosis was verified by a biopsy of the enlarged abdominal lymph nodes with immunohistochemical staining.

摘要

血管免疫母细胞性T细胞淋巴瘤(AITL)是一种独特类型的外周T细胞淋巴瘤,具有一系列临床症状和体征,包括体重减轻、发热、寒战、贫血、皮疹、肝脾肿大、淋巴结病、血小板减少和多克隆高球蛋白血症。AITL的组织学特征也很独特。纯红细胞再生障碍是一种骨髓衰竭,其特征为进行性正细胞性贫血和网织红细胞减少,而无白细胞减少或血小板减少。然而,伴有腹痛和纯红细胞再生障碍的AITL鲜有报道。在此,我们报告1例罕见的伴有腹痛的AITL相关性纯红细胞再生障碍病例。通过对肿大的腹部淋巴结进行活检及免疫组化染色确诊。

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Angioimmunoblastic T-cell lymphoma.血管免疫母细胞性T细胞淋巴瘤
Crit Rev Oncol Hematol. 2008 Dec;68(3):264-71. doi: 10.1016/j.critrevonc.2008.06.012. Epub 2008 Aug 6.

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