Department of Chemistry, IIT Guwahati, Guwahati, Assam, India781039.
Analyst. 2013 Oct 21;138(20):5942-8. doi: 10.1039/c3an00978e. Epub 2013 Aug 9.
The binding interactions of Cu(2+), an essential trace metal ion, and Cd(2+), a deleterious metal ion, with 2-(4'-N,N-dimethylaminophenyl)oxazolo[4,5-b]pyridine (DMAPOP) were studied in acetonitrile and sodium dodecyl sulphate (SDS). The studies show that the surfactant can formulate the metal ions to bind at a specific binding site. In acetonitrile, the Cu(2+) binds at the dimethylamino nitrogen and pyridine nitrogen to form two different types of complexes with DMAPOP. On the other hand, Cd(2+) coordinates through the dimethylamino nitrogen and oxazole nitrogen to form two different types of complexes with DMAPOP in acetonitrile. But SDS effectively controls the binding site and both metal ions bind at the same ring nitrogen in SDS. The binding affinities of both metal ions with DMAPOP vary with the concentration of SDS.
铜（2+），一种必需的痕量金属离子，和镉（2+），一种有害的金属离子，与 2-（4'-N，N-二甲基氨基苯基）恶唑并[4,5-b]吡啶（DMAPOP）在乙腈和十二烷基硫酸钠（SDS）中的结合相互作用进行了研究。研究表明，表面活性剂可以将金属离子组合到特定的结合位点。在乙腈中，铜（2+）与二甲氨基氮和吡啶氮结合，形成两种不同类型的 DMAPOP 配合物。另一方面，镉（2+）通过二甲氨基氮和恶唑氮与 DMAPOP 配位，在乙腈中形成两种不同类型的配合物。但是 SDS 有效地控制了结合位点，两种金属离子都在 SDS 中与同一环氮结合。两种金属离子与 DMAPOP 的结合亲和力随 SDS 浓度的变化而变化。
