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儿童癌症概况:一项多中心研究。

Profile of childhood cancers: a multicentric study.

作者信息

Roy Birendra Nath, Purkait Radheshyam, Ganguly Subir, Samanta Tryambak, Gayen Shibnath, Pal Sumita

机构信息

Department of Paediatric Medicine, NRS Medical College, Kolkata 700014.

出版信息

J Indian Med Assoc. 2012 Dec;110(12):872-5.

Abstract

The incidence of cancer has been increasing steadily in the developing world including India. Childhood cancers are a special entity with different genetic, environmental factors playing a role in their aetiology. The profiles of cancer incidence reflect the racial, cultural and geographical diversity within populations. This article shows the profile of childhood cancer across three medical college hospitals in the state of West Bengal in India and the data were collected from the period between 2008 and 2011. The results showed leukaemia was the most common cancer affecting children followed by lymphoma and retinoblastoma.The profile of childhood cancers showed wide variation among the age groups. Frequency of retinoblastoma, renal tumours, neuroblastoma and hepatic tumours were higher in children less than five years whereas lymphoma, leukaemia, bone tumours and central nervous system tumours were found more in children above five years. As many of common childhood malignancies are curable there is need to have a dedicated paediatric cancer registry for assessing the magnitude of problem in our country as paediatric cancers show wide variation across centres.

摘要

在包括印度在内的发展中世界,癌症发病率一直在稳步上升。儿童癌症是一个特殊的实体,不同的遗传、环境因素在其病因中起作用。癌症发病率概况反映了人群中的种族、文化和地理多样性。本文展示了印度西孟加拉邦三家医学院附属医院的儿童癌症概况,数据收集于2008年至2011年期间。结果显示,白血病是影响儿童最常见的癌症,其次是淋巴瘤和视网膜母细胞瘤。儿童癌症概况在各年龄组中差异很大。视网膜母细胞瘤、肾肿瘤、神经母细胞瘤和肝肿瘤在5岁以下儿童中更为常见,而淋巴瘤白血病、骨肿瘤和中枢神经系统肿瘤在5岁以上儿童中更为常见。由于许多常见的儿童恶性肿瘤是可治愈的所以需要建立一个专门的儿科癌症登记处,以评估我国该问题的严重程度,因为儿科癌症在各中心之间差异很大。

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