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迷走神经巨大神经鞘瘤:一例报告并文献复习

Giant neurilemmoma of the vagus nerve: a case report and review of literature.

作者信息

Dhull Anil Kumar, Kaushal Vivek, Atri Rajeev, Dhankhar Rakesh, Kataria Sant Parkash

机构信息

Department of Radiation Oncology, PGIMS, Rohtak 124001.

出版信息

J Indian Med Assoc. 2012 Dec;110(12):926-8.

Abstract

Cervical vagal neurilemmomas are rare, usually asymptomatic, slow-growing tumours and defined as a benign, encapsulated neoplasm that arises in the nerve fibre. Magnetic resonant imaging (MRI) plays a central role in diagnosing vagal nerve neoplasm and in fact, provides important pre-operative information useful in planning optimal surgical treatment. A rare case of giant neurilemmoma is presented with a large swelling in the right side of the neck associated with breathlessness and paroxysmal cough. X-ray chest revealed large homogenous opacity in apical area of the right lung extending into the lower neck. MRI revealed a large 6 x 8 x 13 cm soft tissue, well defined mass with lobulated contours on the right side of the neck. The mass was pushing sternomastoid muscle anteriorly and carotid artery was pushed anteromedially. The mass was abutting the brachial plexus and compressing internal jugular vein. The mass was extending into the mediastinum up to the level of carina. The mass was also pushing the vessels in superior mediastinum towards left and was compressing the veins. Tumour was extending posterior to trachea and pushing trachea anteriorly and towards left and also compressing it. There was also erosion of adjacent anterior aspect of the right upper ribs. Subclavian artery was also encased by the mass. Multiple enlarged lymph nodes were seen in right cervical area. A provisional diagnosis of malignant schwannoma of right vagus nerve was made. Cytology from the fine needle aspirate of the right lower Cervical region of the swelling revealed features of neurilemmoma. Complete surgical resection is the treatment of choice with excellent prognosis, as the tumour was benign, and recurrence is nearly unknown, so it is possible and indeed recommended to preserve nerve integrity with careful dissection.

摘要

颈迷走神经鞘瘤罕见,通常无症状,生长缓慢,被定义为起源于神经纤维的良性、有包膜的肿瘤。磁共振成像(MRI)在迷走神经肿瘤的诊断中起核心作用,事实上,它提供了重要的术前信息,有助于规划最佳手术治疗方案。本文报告1例罕见的巨大神经鞘瘤病例,患者右侧颈部有一巨大肿物,伴有呼吸困难和阵发性咳嗽。胸部X线显示右肺尖部有一大片均匀的致密影延伸至下颈部。MRI显示右侧颈部有一个6×8×13cm的巨大软组织肿块,边界清晰,轮廓呈分叶状。肿块将胸锁乳突肌向前推,颈动脉被推向前内侧。肿块紧邻臂丛神经并压迫颈内静脉。肿块延伸至纵隔,直至隆突水平。肿块还将上纵隔的血管向左推,并压迫静脉。肿瘤向后延伸至气管后方,将气管向前并向左推,同时压迫气管。右侧上位肋骨相邻的前方也有骨质侵蚀。锁骨下动脉也被肿块包绕。右侧颈部可见多个肿大淋巴结。初步诊断为右侧迷走神经恶性神经鞘瘤。对右侧颈部肿物右下区域进行细针穿刺抽吸的细胞学检查显示为神经鞘瘤特征。由于肿瘤为良性,完整手术切除是首选治疗方法,预后良好,复发几乎罕见,因此通过仔细解剖保留神经完整性是可行的,也是推荐的。

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