Ciriaco Antonella, Russo Angelo, Monzani Daniele, Genovese Elisabetta, Benincasa Paola, Caffo Ernesto, Pini Luigi
J Headache Pain. 2013 Aug 9;14(1):69. doi: 10.1186/1129-2377-14-69.
Recently, an increasing number of articles have appeared on central auditory processing disorders, but in the literature there is only one study that evaluated the possible correlation between migraine in the critical phase and central auditory processing. The aim of our study was to assess the correlation between auditory processing information and childhood primary headaches in the intercritical phase.
This is an observational study. We enrolled 54 patients, 30 with primary headache (migraine and tension headache) and 24 normal controls, matched for sex and age. The mean age at first observation was 9 years 10 months; the duration of observational follow-up was 2 years. Both groups had normal audiological and neurological profiles, normal peripheral hearing acuity and normal cognitive and behavioral skills. We excluded patients who had undergone pharmacological prophylactic treatment for headaches in the 6 months preceding the study and subjects with a frequency of headache lower than one every two months. After enrolment, both groups were analyzed with a computerized test battery for Speech Perception Tests in silence and in noise background to assess speech perception disabilities. In addition, with a test battery of Speech Perception Tests, we compared patients with migraines and tension-type headaches. The non-parametric χ2 test, the Mann-Whitney U-test and the Wilcoxon signed ranks test were used for statistical analysis. P-values <0.05 were considered significant and STATA 10 software was used for statistical analyses.
Our results showed that patients with primary headache (migraine and tension-type headache), had a deficit of auditory processing in noisy background compared to control cases, but we found no significant differences when we compared patients with migraine and tension-type headache.
This is a work in progress and further studies are needed to assess the relationship between the impairment of auditory processing and primary headache, not only to improve the diagnostic approach to primary headache, but also to improve therapeutic intervention.
最近，关于中枢听觉处理障碍的文章越来越多，但文献中仅有一项研究评估了临界期偏头痛与中枢听觉处理之间的可能相关性。我们研究的目的是评估临界间期听觉处理信息与儿童原发性头痛之间的相关性。
这是一项观察性研究。我们纳入了54例患者，其中30例患有原发性头痛（偏头痛和紧张性头痛），24例为正常对照，两组在性别和年龄上相匹配。首次观察时的平均年龄为9岁10个月；观察随访时间为2年。两组的听力学和神经学检查结果均正常，外周听力敏锐度正常，认知和行为技能正常。我们排除了在研究前6个月内接受过头痛药物预防性治疗的患者以及头痛频率低于每两个月一次的受试者。入组后，两组均使用计算机化测试组合进行安静和噪声背景下的言语感知测试，以评估言语感知障碍。此外，通过言语感知测试组合，我们比较了偏头痛患者和紧张型头痛患者。采用非参数χ2检验、曼-惠特尼U检验和威尔科克森符号秩检验进行统计分析。P值<0.05被认为具有统计学意义，使用STATA 10软件进行统计分析。
我们的结果显示，与对照组相比，原发性头痛（偏头痛和紧张型头痛）患者在噪声背景下存在听觉处理缺陷，但在比较偏头痛患者和紧张型头痛患者时，我们未发现显著差异。
这是一项正在进行的工作，需要进一步研究来评估听觉处理障碍与原发性头痛之间的关系，这不仅有助于改进原发性头痛的诊断方法，还能改善治疗干预。
