通过 Rh(III)或 Ru(II)催化的 2-烯基吡啶 C-H 键活化，方便地合成喹啉鎓盐。
A convenient synthesis of quinolizinium salts through Rh(III) or Ru(II)-catalyzed C-H bond activation of 2-alkenylpyridines.
机构信息
Department of Chemistry, National Tsing Hua University, Hsinchu 30013, Taiwan.
出版信息
Chem Commun (Camb). 2013 Oct 4;49(76):8528-30. doi: 10.1039/c3cc45004j.
PMID:23938459
Abstract
An efficient synthesis of quinolizinium salts from 2-vinylpyridines and alkynes via Rh(III) or Ru(II)-catalyzed C-H activation and annulation reaction is described. A possible mechanism involving pyridine assisted vinylic ortho-C-H activation, alkyne insertion and reductive elimination is proposed.
摘要
通过 Rh(III)或 Ru(II)催化的 C-H 活化和环化反应，从 2-乙烯基吡啶和炔烃高效合成喹啉鎓盐。提出了一种可能的机制，涉及吡啶辅助的乙烯基邻位 C-H 活化、炔烃插入和还原消除。
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