[单侧上尿路移行细胞癌肾移植患者预防性对侧肾输尿管切除术的必要性]
[Necessity of prophylactic contralateral nephroureterectomy in the renal transplantation patients with transitional cell carcinoma of unilateral upper urinary tract].
作者信息
Tian Ye, Hou Hai-jun, Guo Yu-wen, Zhang Lei, Lin Jun, Zhu Yi-chen, Sun Wen, Xie Ze Lin
机构信息
Department of Urology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China.
出版信息
Beijing Da Xue Xue Bao Yi Xue Ban. 2013 Aug 18;45(4):558-61.
OBJECTIVE
To discuss the necessity of prophylactic contralateral nephroureterectomy in renal transplantation patients with upper urinary tract transitional cell carcinoma (TCC).
METHODS
In our study 15 renal transplantation patients with upper urinary tract TCC were involved from Dec.2006 to May 2013. All the patients received prophylactic contralateral nephroureterectomy 3 months after their last nephroureterectomy. A retrospective analysis was performed.
RESULTS
TCC of upper urinary tract was confirmed by postoperative pathology in all the 15 cases .Similarly, TCC of contralateral upper urinary tract was detected in 7 of these cases (46.7%), and 13 survived after 36 months' follow-up (86.7%).
CONCLUSION
In the renal transplantation patient with unilateral upper urinary tract TCC, the possibility of contralateral upper urinary tract TCC is high, thus the necessity of prophylactic contratateral nephroureterectomy is certain.
目的
探讨肾移植合并上尿路移行细胞癌（TCC）患者行预防性对侧肾输尿管切除术的必要性。
方法
本研究纳入2006年12月至2013年5月期间15例肾移植合并上尿路TCC患者。所有患者在最后一次肾输尿管切除术后3个月接受预防性对侧肾输尿管切除术。进行回顾性分析。
结果
15例患者术后病理均确诊为上尿路TCC。同样，其中7例（46.7%）检测到对侧上尿路TCC，36个月随访后13例存活（86.7%）。
结论
对于单侧上尿路TCC的肾移植患者，对侧上尿路发生TCC的可能性较高，因此预防性对侧肾输尿管切除术确有必要。
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