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二极管激光与铥激光经尿道前列腺剜除术治疗良性前列腺增生的比较

[Comparison of the diode laser and the thulium laser in transurethral enucleation of the prostate for treatment of benign prostatic hyperplasia].

作者信息

Zhang Feng-bo, Shao Qiang, Tian Ye

机构信息

Department of Urology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China.

出版信息

Beijing Da Xue Xue Bao Yi Xue Ban. 2013 Aug 18;45(4):592-6.

Abstract

OBJECTIVE

To compare the validity and safety of diode laser and thulium laser transurethral enucleation of the prostate in benign prostatic hyperplasia (BPH) patients.

METHODS

In our study, 63 BPH patients treated with transurethral enucleation of the prostate were divided randomly into 2 groups by diode laser (Di group) or thulium laser (Thu group) respectively. The operation time, bleeding volume, electrolyte, international prostatic symptomatic score (IPSS), post-voiding residual volume (PVR) and maximum urine flow rate (Qmax) were recorded and compared.

RESULTS

No difference was found in the 2 groups in basic preoperative characteristics. Di group was superior to Thu group in mean operation time [(61.5±19.6) min vs. (71.4±16.5) min, P=0.026] notwithstanding little clinical sense. The mean time of removing catheter was 2.1 d and 2.3 d respectively. No difference in either electrolyte decrease or hemoglobin decrease [(5.0±1.1 g/L) vs. (4.4±0.9) g/L, P=0.32] peri-operation between the 2 groups were found and no transurethral resection (TUR) syndrome was encountered. Lower urinary tract symptom (LUTS) in both the groups were released the 1st and 3nd months post-operation effectively in IPSS, PVR and Qmax respectively and comparable (P>0.05).

CONCLUSION

Both the Diode laser and the Thulium laser transurethral enucleation of the prostate released the LUTS effectively in BPH patients and comparable in the short-time follow-up. Further study about late complications related to enucleation is necessary.

摘要

目的

比较二极管激光和铥激光经尿道前列腺剜除术治疗良性前列腺增生(BPH)患者的有效性和安全性。

方法

在本研究中,63例行经尿道前列腺剜除术的BPH患者被随机分为两组,分别接受二极管激光治疗(Di组)或铥激光治疗(Thu组)。记录并比较手术时间、出血量、电解质、国际前列腺症状评分(IPSS)、排尿后残余尿量(PVR)和最大尿流率(Qmax)。

结果

两组术前基本特征无差异。Di组平均手术时间优于Thu组[(61.5±19.6)分钟对(71.4±16.5)分钟,P = 0.026],尽管临床意义不大。平均拔管时间分别为2.1天和2.3天。两组围手术期电解质降低或血红蛋白降低情况无差异[(5.0±1.1)g/L对(4.4±0.9)g/L,P = 0.32],且未发生经尿道电切(TUR)综合征。两组下尿路症状(LUTS)在术后第1个月和第3个月分别在IPSS、PVR和Qmax方面有效缓解,且具有可比性(P>0.05)。

结论

二极管激光和铥激光经尿道前列腺剜除术均能有效缓解BPH患者的LUTS,且在短期随访中效果相当。有必要进一步研究与剜除术相关的晚期并发症。

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