Fan Hua, Li Han-zhong, Zhang Yu-shi, Zhang Xue-bin, Shi Bing-bing
Department of Urology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China.
Beijing Da Xue Xue Bao Yi Xue Ban. 2013 Aug 18;45(4):654-6.
To investigate the clinicopathological characteristics of metanephric adenoma (MA), we analyzed the clinical and pathological data of metanephric adenoma. A 39-year old woman with asymptomatic right kidney tumor for 4 years was admitted to the hospital. A tumor with the largest diameter of 28 mm in the right kidney was homogeneously enhanced on CT. The tumor was distinctly increased as compared with 4 years before. The diagnosis was right kidney tumor. Nephron-sparing surgery was given after general anaesthesia. And the relative literature was reviewed. The tumor was homogeneous, with integrity tegument, and a grey cutting surface. Histopathologically, the tumor cells formed an adenoid or papillary pattern and contained psammoma bodies. Immunohistologically, they were positive for AE1/AE3, vimentin and WT1, negative for CK7, EMA and RCC. Pathological diagnosis was metanephric adenoma. The follow-up data of 24 months were available and without recurrence. MA is peculiar. It is difficult to get the final diagnosis of MA only by imaging characters. Nephron-sparing surgery is eligible for the treatment of MA. Considering the uncertainty of the biological behavior and cellular origin of MA, a long-term active surveillance is necessary.
为了研究后肾腺瘤（MA）的临床病理特征，我们分析了后肾腺瘤的临床和病理资料。一名39岁女性因右肾无症状肿瘤4年入院。右肾一个最大直径为28mm的肿瘤在CT上呈均匀强化。与4年前相比，肿瘤明显增大。诊断为右肾肿瘤。全身麻醉后行保肾手术。并复习了相关文献。肿瘤质地均匀，包膜完整，切面呈灰白色。组织病理学上，肿瘤细胞形成腺样或乳头状结构，并含有砂粒体。免疫组织化学检查显示，它们对AE1/AE3、波形蛋白和WT1呈阳性，对CK7、EMA和RCC呈阴性。病理诊断为后肾腺瘤。有24个月的随访资料，无复发。后肾腺瘤很特殊。仅通过影像学特征很难做出后肾腺瘤的最终诊断。保肾手术适用于后肾腺瘤的治疗。考虑到后肾腺瘤生物学行为和细胞起源的不确定性，长期积极监测是必要的。
