Department of Cell Biology, School of Life Sciences, Shaanxi Normal University, Xi'an, Shaanxi, China.
J Cell Physiol. 2014 Mar;229(3):287-91. doi: 10.1002/jcp.24449.
Numerous evidences have indicated that a signal system is composed by signal pathways, each pathway is composed by sub-pathways, and the sub-pathway is composed by the original signal terminals initiated with a protein/gene. We infer the terminal signals merged signal transduction system as "signal basin". In this article, we discussed the composition and regulation of signal basins, and the relationship between the signal basin control and triple W of spatiotemporal cell biology. Finally, we evaluated the importance of the systemic regulation to gene expression by signal basins under triple W. We hope our discussion will be the beginning to cause the attention for this area from the scientists of life science.
大量证据表明，信号系统由信号通路组成，每条通路由子通路组成，而子通路由以蛋白质/基因为起始的原始信号终端组成。我们将终端信号汇集成信号盆地。在本文中，我们讨论了信号盆地的组成和调节，以及信号盆地控制与时空细胞生物学的三重 W 之间的关系。最后，我们评估了信号盆地在三重 W 下对基因表达的系统调节的重要性。我们希望我们的讨论将引起生命科学领域科学家对这一领域的关注。
