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热成像——一种可行的乳腺癌筛查方法?

Thermography--a feasible method for screening breast cancer?

作者信息

Kolarić Darko, Herceg Zeljko, Nola Iskra Alexandra, Ramljak Vesna, Kulis Tomislav, Holjevac Jadranka Katancić, Deutsch Judith A, Antonini Svetlana

机构信息

"Ruder Bosković" Institute, Centre for Informatics and Computing, Zagreb, Croatia.

出版信息

Coll Antropol. 2013 Jun;37(2):583-8.

Abstract

Potential use of thermography for more effective detection of breast carcinoma was evaluated on 26 patients scheduled for breast carcinoma surgery. Ultrasonographic scan, mammography and thermography were performed at the University Hospital for Tumors. Thermographic imaging was performed using a new generation of digital thermal cameras with high sensitivity and resolution (ThermoTracer TH7102WL, NEC). Five images for each patient were recorded: front, right semi-oblique, right oblique, left- semi oblique and left oblique. While mammography detected 31 changes in 26 patients, thermography was more sensitive and detected 6 more changes in the same patients. All 37 changes were subjected to the cytological analysis and it was found that 16 of samples were malignant, 8 were suspected malignant and 11 were benign with atypia or proliferation while only 2 samples had benign findings. The pathohistological method (PHD) recorded 75.75% malignant changes within the total number of samples. Statistical analysis of the data has shown a probability of a correct mammographic finding in 85% of the cases (sensitivity of 85%, specificity of 84%) and a probability of a correct thermographic finding in 92% of the cases (sensitivity of 100%, specificity of 79%). As breast cancer remains the most prevalent cancer in women and thermography exhibited superior sensitivity, we believe that thermography should immediately find its place in the screening programs for early detection of breast carcinoma, in order to reduce the sufferings from this devastating disease.

摘要

对26名计划进行乳腺癌手术的患者评估了热成像技术在更有效检测乳腺癌方面的潜在用途。在肿瘤大学医院进行了超声扫描、乳房X线摄影和热成像检查。使用具有高灵敏度和分辨率的新一代数字热像仪(ThermoTracer TH7102WL,NEC)进行热成像。为每位患者记录了五张图像:正面、右半斜位、右斜位、左半斜位和左斜位。乳房X线摄影在26名患者中检测到31处病变,而热成像更敏感,在同一患者中又检测到6处病变。对所有37处病变进行了细胞学分析,发现其中16个样本为恶性,8个疑似恶性,11个为良性但有非典型性或增生,只有2个样本为良性。病理组织学方法(PHD)在样本总数中记录到75.75%的恶性病变。数据的统计分析表明,乳房X线摄影在85%的病例中有正确发现的概率(灵敏度为85%,特异性为84%),热成像在92%的病例中有正确发现的概率(灵敏度为100%,特异性为79%)。由于乳腺癌仍然是女性中最常见的癌症,且热成像表现出更高的灵敏度,我们认为热成像应立即在乳腺癌早期检测的筛查项目中占有一席之地,以减轻这种毁灭性疾病带来的痛苦。

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