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血吸虫病中的芳基硫酸酯酶

Arylsulfatases in bilharziasis.

作者信息

Khafagy E Z, Raziky H E, Galal A F

出版信息

Egypt J Bilharz. 1976;3(2):213-9.

PMID:23942
Abstract

Arylsulfatase A and B in urine have been estimated in 18 normal subjects and 50 bilharziasis patients. The bilharziasis patients were divided into two groups according to the type of infeciton. Those with bilharziasis haematobian type of infection and those with the bilharziasis mansoni type. Each group was further subdivided into subgroups according to the severity and progress of the disease. The activities of arylsulfatase A and B were significantly elevated in all the groups of patients studied and it is evident that there is a progressive increase with the progress of the disease in both types of bilharziasis infections (the haematobian and mansoni types). Liver dysfunction consequent of bilharzial infestation appears to take part in the mechanism of induction of the bilharzial bladder cancer.

摘要

对18名正常人和50名血吸虫病患者的尿液中的芳基硫酸酯酶A和B进行了测定。根据感染类型,将血吸虫病患者分为两组。分别是埃及血吸虫感染型和曼氏血吸虫感染型。每组再根据疾病的严重程度和进展进一步细分亚组。在所研究的所有患者组中,芳基硫酸酯酶A和B的活性均显著升高,显然,在两种类型的血吸虫感染(埃及血吸虫和曼氏血吸虫)中,随着疾病的进展,其活性都在逐渐增加。血吸虫感染导致的肝功能障碍似乎参与了血吸虫性膀胱癌的诱导机制。

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