Schneede P, Waidelich R
Urologische Klinik, Klinikum Memmingen, Bismarckstr. 23, 87700, Memmingen, Deutschland,
Urologe A. 2013 Sep;52(9):1329-36: quiz 1337-8. doi: 10.1007/s00120-013-3257-7.
The information presented in this article summarizes some of the basic knowledge on human papillomavirus (HPV) infections and the consequences particularly in men. According to current understanding most HPV infections are latent and transient in immunocompetent patients but some will persist. Predominantly due to the different oncogenic potential of various HPV types, persisting infections can give rise to benign or malignant neoplasms in both genders. Current controversies, such as the need for HPV testing in men or routine male HPV vaccination will be discussed. High-risk male populations, e.g. men who have sex with men (MSM) and HIV positive men, merit special attention from urologists in the future. The groups of HIV positive MSMs are at an extremely high risk of developing anal cancer that currently even exceeds the highest reported incidence of cervical cancer.
本文所呈现的信息总结了一些关于人乳头瘤病毒(HPV)感染的基本知识,尤其是其对男性的影响及后果。根据目前的认识,大多数HPV感染在免疫功能正常的患者中是潜伏性和一过性的,但有些感染会持续存在。主要由于不同类型HPV的致癌潜力不同,持续感染可在男女两性中引发良性或恶性肿瘤。本文还将讨论当前的一些争议问题,如男性HPV检测的必要性或常规男性HPV疫苗接种等。高危男性群体,如男男性行为者(MSM)和HIV阳性男性,未来值得泌尿外科医生给予特别关注。HIV阳性的男男性行为者群体患肛门癌的风险极高,目前甚至超过了报道的宫颈癌最高发病率。