MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou, 310027, P.R. China.
Adv Mater. 2013 Oct 25;25(40):5814-8. doi: 10.1002/adma.201302875. Epub 2013 Aug 14.
Multilayer microcapsules with a biconcave discoidal shape mimicking red blood cells (RBCs) are fabricated. The structure of the RBC-like microcapsules is verified by scanning electron and confocal laser scanning microscopies. The capsules show elastic deformation after being forced through a microcapillary with a smaller diameter, exhibiting a high recovery ratio of ≈90%. When the capsules are coated with hemoglobin (Hb),they are able to reversibly bind and release oxygen.
制备了具有模仿红细胞 (RBC) 双凹盘形的多层微胶囊。通过扫描电子显微镜和共聚焦激光扫描显微镜验证了 RBC 样微胶囊的结构。这些胶囊在被迫通过直径较小的微管后会发生弹性变形，表现出约 90%的高回复率。当胶囊表面覆盖血红蛋白 (Hb) 时，它们能够可逆地结合和释放氧气。
