Wolfe Diana S, Williams Shauna F, Ross Michael G, Beall Marie H, Apuzzio Joseph J
Department of Obstetrics and Gynecology, Albert Einstein College of Medicine, Montefiore Medical Center, New York, New York.
AJP Rep. 2013 May;3(1):13-6. doi: 10.1055/s-0032-1329127. Epub 2013 Jan 25.
Objective To investigate potential predictive symptoms of late postpartum eclampsia (LPE). Study Design Retrospective review of patients delivered at a single academic medical center and diagnosed with eclampsia greater than 48 hours postdelivery. Results Among 19 patients with eclampsia, 5 (26%) patients with confirmed eclampsia seized greater than 48 hours after delivery. None of these patients showed evidence of preeclampsia intrapartum or immediately postpartum and none received intrapartum magnesium sulfate. Prior to seizure activity, 4 of 5 (80%) patients had increased blood pressure and 2 of 5 (40%) had central nervous system symptoms (headache and visual changes). Conclusion Gestational hypertension (GHTN) may be a risk factor for LPE. Consideration of seizure prophylaxis for patients with GHTN may facilitate the prevention of LPE.
目的 研究晚发型产后子痫（LPE）的潜在预测症状。研究设计 对在单一学术医疗中心分娩且产后48小时后被诊断为子痫的患者进行回顾性研究。结果 在19例子痫患者中，5例（26%）确诊子痫的患者在产后48小时后发作。这些患者均未在产时或产后立即出现先兆子痫的迹象，也均未在产时接受硫酸镁治疗。在癫痫发作前，5例患者中有4例（80%）血压升高，5例中有2例（40%）出现中枢神经系统症状（头痛和视觉改变）。结论 妊娠期高血压（GHTN）可能是LPE的一个危险因素。考虑对GHTN患者进行癫痫预防可能有助于预防LPE。
