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常见睡眠障碍的管理。

Management of common sleep disorders.

机构信息

Mayo Clinic, Rochester, MN, USA.

出版信息

Am Fam Physician. 2013 Aug 15;88(4):231-8.

Abstract

Sleep disorders are common and affect sleep quality and quantity, leading to increased morbidity. Patients with sleep disorders can be categorized as those who cannot sleep, those who will not sleep, those with excessive daytime sleepiness, and those with increased movements during sleep. Insomnia, defined as difficulty initiating or maintaining sleep that results in daytime impairment, is diagnosed using history findings and treated with cognitive behavior therapy, with or without sleep hypnotics. Restless legs syndrome is characterized by an urge to move the legs that worsens with rest, is relieved by movement, and often occurs in the evening or at night. Restless legs syndrome is treated based on the frequency of symptoms. Narcolepsy is characterized by excessive sleepiness, cataplexy, hypnagogic or hypnopompic hallucinations, and sleep paralysis. It is diagnosed using a sleep log or actigraphy, followed by overnight polysomnography and a multiple sleep latency test. Narcolepsy is treated with stimulants, such as modafinil; selective serotonin reuptake inhibitors; or gamma hydroxybutyric acid (sodium oxybate). Patients with snoring and witnessed apneas may have obstructive sleep apnea, which is diagnosed using overnight polysomnography. Continuous positive airway pressure is the most common and effective treatment for obstructive sleep apnea. Rapid eye movement sleep behavior disorder is characterized by increased muscle tone during rapid eye movement sleep, resulting in the patient acting out dreams with possible harmful consequences. It is diagnosed based on history and polysomnography findings, and treated with environmental safety measures and melatonin or clonazepam.

摘要

睡眠障碍很常见,会影响睡眠质量和数量,导致发病率增加。睡眠障碍患者可分为难以入睡、无法入睡、白天过度嗜睡和睡眠中运动增加的患者。失眠症定义为入睡或维持睡眠困难,导致白天功能障碍,通过病史发现进行诊断,并采用认知行为疗法治疗,可辅以或不辅以睡眠催眠药物。不宁腿综合征的特征是腿部有强烈的移动欲望,休息时加重,活动时缓解,常发生在晚上或夜间。不宁腿综合征根据症状的频率进行治疗。发作性睡病的特征是过度嗜睡、猝倒、催眠或催眠幻觉和睡眠瘫痪。通过睡眠日志或活动记录仪进行诊断,然后进行整夜多导睡眠图和多次睡眠潜伏期试验。发作性睡病用兴奋剂(如莫达非尼)、选择性 5-羟色胺再摄取抑制剂或γ-羟基丁酸(羟丁酸钠)治疗。打鼾和目击呼吸暂停的患者可能患有阻塞性睡眠呼吸暂停,通过整夜多导睡眠图进行诊断。持续气道正压通气是治疗阻塞性睡眠呼吸暂停最常用和最有效的方法。快速眼动睡眠行为障碍的特征是快速眼动睡眠期间肌肉张力增加,导致患者在梦中做出可能有危险后果的动作。它根据病史和多导睡眠图发现进行诊断,并通过环境安全措施和褪黑素或氯硝西泮进行治疗。

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