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急诊乳房游离皮瓣挽救术的系统方法:临床结果、算法及文献综述

A systematic approach to emergent breast free flap takeback: Clinical outcomes, algorithm, and review of the literature.

作者信息

Khansa Ibrahim, Chao Albert H, Taghizadeh Maakan, Nagel Theodore, Wang Duane, Tiwari Pankaj

机构信息

The Ohio State University Wexner Medial Center, Department of Plastic Surgery, Columbus, OH 43212, USA.

The Ohio State University Wexner Medial Center, Department of Plastic Surgery, Columbus, OH.

出版信息

Microsurgery. 2013 Oct;33(7):505-13. doi: 10.1002/micr.22151. Epub 2013 Aug 14.

Abstract

BACKGROUND

Few evidence-based and detailed algorithms exist on the management of failing breast free flaps, including use of the numerous salvage tools that are available. The purpose of this study was to analyze our outcomes with an algorithmic approach to breast free flap salvage after vascular compromise. A review of the literature is also presented.

METHODS

A retrospective review of all breast free flaps performed at our institution between 2007 and 2012 was performed. Flaps with intraoperative and postoperative vascular complications were analyzed.

RESULTS

A total of 612 microsurgical breast reconstructions in 442 patients were reviewed. Of these, 72 (11.8%) flaps had intraoperative vascular complications, and 36 (5.9%) had postoperative vascular complications. The total flap loss rate was 2.8%. The most commonly used salvage modalities were anastomotic revision (72%), heparin irrigation (72%), systemic heparin (37%), Fogarty catheter thrombectomy (17.6%), thrombolytics (13%), and indocyanine green angiography (10.2%). In 53 (49.1%) cases, flap salvage involved use of 1 modality, whereas in 55 (50.9%) cases multiple modalities were used. Factors associated with failure of these flap salvage tools included intraoperative arterial rather than postoperative arterial compromise (P = 0.01), and situations requiring use of a greater number of salvage modalities (P < 0.001).

CONCLUSIONS

We found that intraoperative compromise had significantly better prognosis than postoperative compromise. By organizing the numerous salvage modalities available to microsurgeons into a well-defined algorithm that is supported by the literature, we have established a best practices protocol that has achieved flap salvage rates that compare favorably to the published literature.

摘要

背景

在处理失败的乳房游离皮瓣时,包括使用众多可用的挽救工具,几乎没有基于证据的详细算法。本研究的目的是分析我们采用算法方法挽救血管受损后的乳房游离皮瓣的结果。同时还对文献进行了综述。

方法

对2007年至2012年在我们机构进行的所有乳房游离皮瓣手术进行回顾性研究。分析术中及术后出现血管并发症的皮瓣。

结果

共回顾了442例患者的612例显微外科乳房重建手术。其中,72例(11.8%)皮瓣有术中血管并发症,36例(5.9%)有术后血管并发症。皮瓣总丢失率为2.8%。最常用的挽救方式是吻合口修复(72%)、肝素冲洗(72%)、全身肝素治疗(37%)、Fogarty导管取栓术(17.6%)、溶栓治疗(13%)和吲哚菁绿血管造影(10.2%)。在53例(49.1%)病例中,皮瓣挽救采用了1种方式,而在55例(50.9%)病例中采用了多种方式。这些皮瓣挽救工具失败的相关因素包括术中动脉而非术后动脉受损(P = 0.01),以及需要使用更多挽救方式的情况(P < 0.001)。

结论

我们发现术中受损的预后明显优于术后受损。通过将显微外科医生可用的众多挽救方式组织成一个有文献支持的明确算法,我们建立了一个最佳实践方案,其皮瓣挽救率与已发表的文献相比具有优势。

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