Karp J K, Davis A, Read P J, Mashayekh A, Bombonati A, Palazzo F
Thomas Jefferson University Hospital, Methodist Division, Philadelphia, PA 19148, USA.
Pathologica. 2013 Apr;105(2):59-61.
Pulse granuloma is a rare, benign entity that most likely represents a reaction to vegetable material and is characterized by hyaline rings and foreign-body giant cells. We report a case of a pulse granuloma involving Meckel's diverticulum. The patient presented with abdominal pain and radiological findings consistent with Meckel's diverticulum. Microscopic examination of the resected tissue confirmed diagnosis of Meckel's diverticulum with small bowel mucosa. Peridiverticular foreign-body giant cells, hyaline rings and circular structures containing calcified basophilic granules were also identified, consistent with pulse granuloma. Pulse granulomas have been reported in a variety of locations, most commonly in the oral cavity. To the best of our knowledge, this is the first reported example of pulse granuloma in Meckel's diverticulum. Familiarity with pulse granuloma allows for the timely and accurate diagnosis of this entity, particularly in sites not previously described in the literature.
脉冲肉芽肿是一种罕见的良性病变，很可能是对植物性物质的一种反应，其特征为透明环和异物巨细胞。我们报告一例累及梅克尔憩室的脉冲肉芽肿病例。患者表现为腹痛，影像学检查结果与梅克尔憩室相符。对切除组织的显微镜检查证实为伴有小肠黏膜的梅克尔憩室。憩室周围还发现了异物巨细胞、透明环以及含有钙化嗜碱性颗粒的圆形结构，符合脉冲肉芽肿表现。脉冲肉芽肿已报道见于多种部位，最常见于口腔。据我们所知，这是梅克尔憩室中脉冲肉芽肿的首例报道。熟悉脉冲肉芽肿有助于及时准确地诊断该病变，尤其是在文献中未曾描述过的部位。
