Ceballos P I, Penneys N S, Acosta R
Department of Dermatology, University of Miami School of Medicine, FL 33101.
J Am Acad Dermatol. 1990 Aug;23(2 Pt 2):331-4. doi: 10.1016/0190-9622(90)70215-4.
Aggressive digital papillary adenocarcinoma is a rare neoplasm of eccrine sweat gland origin. An acral location and a high recurrence rate are characteristic features. Its histopathologic features are distinctive, and the tumor expresses carcinoembryonic and S-100 protein antigens. We demonstrated immunoreactivity of the tumor to ferritin antibody, a new immunohistologic marker for sweat gland malignancies.
侵袭性指状乳头状腺癌是一种起源于小汗腺的罕见肿瘤。肿瘤好发于肢端部位,且复发率高是其特征性表现。其组织病理学特征独特,肿瘤表达癌胚抗原和S-100蛋白抗原。我们证实了该肿瘤对铁蛋白抗体具有免疫反应性,铁蛋白抗体是一种用于汗腺恶性肿瘤的新免疫组织学标志物。