Arq Bras Cardiol. 2013 Sep;101(3):197-204. doi: 10.5935/abc.20130163. Epub 2013 Aug 14.
In non-ST-segment elevation acute coronary syndrome (ACS), the likelihood of adverse events should be estimated. Guidelines recommend risk stratification models for that purpose. The Dante Pazzanese risk score (DANTE score) is a simple risk stratification model composed with the following variables: age increase (0 to 9 points); history of diabetes mellitus (2 points) or stroke (4 points); no use of angiotensin-converting-enzyme inhibitor (1 point); creatinine elevation (0 to 10 points); combination of troponin elevation and ST-segment depression (0 to 4 points).
To validate the DANTE score in patients with non-ST-segment elevation ACS.
Prospective, observational study including 457 patients, from September 2009 to October 2010. The patients were grouped in risk categories according to the original model score as follows: very low; low; intermediate; and high. The predictive ability of the score was assessed by using C-statistics.
The sample comprised 291 (63.7%) men, the mean age being 62.1 years (SD=11.04). The event death or (re)infarction in 30 days was observed in 17 patients (3.7%). Progressive increase in the proportion of events was observed as the score increased: very low risk = 0.0%; low risk = 3.9%; intermediate risk = 10.9%; high risk = 60.0%; p < 0.0001. C-statistics was 0.87 (95% CI: 0.81-0.94; p < 0.0001).
DANTE score showed an excellent capacity to predict the specific events, and can be incorporated to the prognostic assessment of patients with non-ST-segment elevation ACS.
在非 ST 段抬高型急性冠状动脉综合征（ACS）中，应估计不良事件的可能性。为此，指南推荐风险分层模型。但丁·帕萨泽风险评分（DANTE 评分）是一种简单的风险分层模型，由以下变量组成：年龄增加（0 至 9 分）；糖尿病史（2 分）或中风（4 分）；未使用血管紧张素转换酶抑制剂（1 分）；肌酐升高（0 至 10 分）；肌钙蛋白升高和 ST 段压低的组合（0 至 4 分）。
验证 DANTE 评分在非 ST 段抬高型 ACS 患者中的有效性。
前瞻性、观察性研究，纳入 2009 年 9 月至 2010 年 10 月的 457 例患者。根据原始模型评分将患者分为低危、中危和高危。通过 C 统计量评估评分的预测能力。
样本包括 291 名（63.7%）男性，平均年龄为 62.1 岁（标准差=11.04）。30 天内观察到 17 例死亡或（再）梗死事件（3.7%）。随着评分的增加，观察到事件的比例逐渐增加：低危=0.0%；中危=3.9%；高危=10.9%；极高危=60.0%；p<0.0001。C 统计量为 0.87（95%置信区间：0.81-0.94；p<0.0001）。
DANTE 评分对特定事件的预测能力较强，可纳入非 ST 段抬高型 ACS 患者的预后评估。
