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药物洗脱支架血栓形成的冠状动脉内溶栓“挽救治疗”

"Rescue administration" of intracoronary thrombolytic therapy for drug-eluting stent thrombosis.

作者信息

Karabay C Y, Kocabay G, Kalayci A, Tasar O, Kirma C

机构信息

Department of Cardiology, Kartal Kosuyolu Yuksek Ihtisas Heart Education and Research Hospital, Kartal, Istanbul, Turkey.

出版信息

Herz. 2014 Aug;39(5):647-50. doi: 10.1007/s00059-013-3876-1. Epub 2013 Jul 24.

Abstract

Stent thrombosis is an example of device-induced, platelet-mediated arterial thrombosis with a potentially fatal adverse event that often leads to myocardial infarction and/or death. The optimal treatment of patients with drug-eluting stent thrombosis in whom mechanical thrombectomy has failed is not established. This case demonstrates the usefulness of intracoronary thrombolysis after failed mechanical thrombectomy in patients with stent thrombosis. To our knowledge, this is the first report on using intracoronary thrombolysis in this specific situation.

摘要

支架内血栓形成是一种由器械诱导、血小板介导的动脉血栓形成,是一种具有潜在致命性的不良事件,常导致心肌梗死和/或死亡。对于机械血栓切除术失败的药物洗脱支架内血栓形成患者,最佳治疗方案尚未确定。本病例证明了在支架内血栓形成患者中,机械血栓切除术失败后进行冠状动脉内溶栓的有效性。据我们所知,这是关于在这种特定情况下使用冠状动脉内溶栓的首次报告。

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