IL-2/anti-IL-2 complex: a novel strategy of in vivo regulatory T cell expansion in renal injury.
作者信息
Wang Yuan Min, Alexander Stephen I
机构信息
Centre for Kidney Research, Children's Hospital at Westmead, Sydney, Australia.
出版信息
J Am Soc Nephrol. 2013 Oct;24(10):1503-4. doi: 10.1681/ASN.2013070718. Epub 2013 Aug 15.
Abstract
摘要
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IL-2/anti-IL-2 complex attenuates renal ischemia-reperfusion injury through expansion of regulatory T cells.白细胞介素-2/抗白细胞介素-2 复合物通过扩增调节性 T 细胞减轻肾缺血再灌注损伤。
J Am Soc Nephrol. 2013 Oct;24(10):1529-36. doi: 10.1681/ASN.2012080784. Epub 2013 Jul 5.
2
Regulatory T cells participate in CD39-mediated protection from renal injury.调节性 T 细胞参与 CD39 介导的肾损伤保护。
Eur J Immunol. 2012 Sep;42(9):2441-51. doi: 10.1002/eji.201242434.
3
IL-2/IL-2Ab complexes induce regulatory T cell expansion and protect against proteinuric CKD.IL-2/IL-2Ab 复合物诱导调节性 T 细胞扩增并防止蛋白尿性 CKD。
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A superagonistic monoclonal antibody for CD28 ameliorates crescentic glomerulonephritis in wistar-kyoto rats.一种针对 CD28 的超激动性单克隆抗体可改善 Wistar-Kyoto 大鼠的新月体性肾小球肾炎。
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Cutting edge: mechanisms of IL-2-dependent maintenance of functional regulatory T cells.前沿：IL-2 依赖性维持功能性调节性 T 细胞的机制。
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