Torio Michiko, Sanefuji Masafumi, Hara Toshiro
Department of Pediatrics, Fukuoka Red Cross Hospital, Fukuoka.
No To Hattatsu. 2013 Jul;45(4):314-7.
Febrile myoclonus is a benign neurological symptom induced by fever. The physiological mechanism is unknown. We herein report a 1 year and 7 months old male patient with intermittent jerks of the whole body during a high fever caused by acute otitis media. He experienced more than 50 jerks over a period of 2 days. The jerks appeared only during sleep. He showed no impairment of consciousness and no abnormalities in neurological examination, blood examination, electroencephalogram, or brain MRI findings. We diagnosed him with febrile myoclonus. The myoclonic jerks disappeared as the fever decreased without neurological sequelae. To the best of our knowledge, febrile myoclonus only during sleep has never been reported. To clarify the pathophysiology of febrile myoclonus, we should focus on the relationship between the myoclonus and the sleep/awake states.
热性肌阵挛是一种由发热引起的良性神经症状。其生理机制尚不清楚。我们在此报告一名1岁7个月大的男性患者，在急性中耳炎引起的高热期间出现全身间歇性抽搐。在2天的时间里，他出现了50多次抽搐。这些抽搐仅在睡眠期间出现。他意识无损害，神经检查、血液检查、脑电图或脑部MRI检查均无异常。我们诊断他为热性肌阵挛。随着发热消退，肌阵挛性抽搐消失，未留下神经后遗症。据我们所知，仅在睡眠期间出现的热性肌阵挛从未有过报道。为了阐明热性肌阵挛的病理生理学，我们应关注肌阵挛与睡眠/觉醒状态之间的关系。
