Department of Anaesthesiology and Intensive Care, A. Gemelli Hospital, Rome, Italy.
Anaesthesia. 2013 Nov;68(11):1141-7. doi: 10.1111/anae.12386. Epub 2013 Aug 19.
The aim of this study was to investigate whether auditory presentation of a story during general anaesthesia might influence stress hormone changes and thus affecting dream recall and/or implicit memory. One hundred and ten patients were randomly assigned either to hear a recording of a story through headphones or to have routine care with no auditory recording while undergoing laparoscopic cholecystectomy. Anaesthesia was standardised. Blood samples for cortisol and prolactin assays were collected 20 min before anaesthesia and 5 min after pneumoperitoneum. Dream recall and explicit/implicit memory were investigated upon awakening from anaesthesia and approximately 24 h after the end of the operation. Auditory presentation was associated with lower intra-operative serum prolactin concentration compared with control (p = 0.0006). Twenty-seven patients with recall of dreaming showed higher intra-operative prolactin (p = 0.004) and lower cortisol (p = 0.03) concentrations compared with those without dream recall. The knowledge of this interaction might be useful in the quest to ensure postoperative amnesia.
本研究旨在探讨全身麻醉期间听觉呈现故事是否会影响应激激素变化，从而影响梦境回忆和/或内隐记忆。110 名患者被随机分为听耳机录音组或常规护理无听觉记录组，在接受腹腔镜胆囊切除术时接受相应处理。麻醉标准化。在麻醉前 20 分钟和气腹后 5 分钟采集用于皮质醇和催乳素测定的血样。在从麻醉中苏醒后和手术结束后约 24 小时调查梦境回忆和外显/内隐记忆。与对照组相比，听觉呈现与术中催乳素浓度较低相关（p = 0.0006）。27 名有梦境回忆的患者显示术中催乳素浓度较高（p = 0.004）和皮质醇浓度较低（p = 0.03）。了解这种相互作用可能有助于确保术后遗忘。
