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风湿性疾病骨科手术发病率的变化:影响因素。

Changing incidence of orthopedic surgery in rheumatic disease: contributing factors.

机构信息

Division of Rheumatology, Hospital for Special Surgery, 535 East 70th Street, New York, NY 10021, USA,

出版信息

Curr Rheumatol Rep. 2013 Oct;15(10):365. doi: 10.1007/s11926-013-0365-8.

Abstract

Rheumatic diseases are multisystem conditions that predominantly affect the musculoskeletal system, leading to soft tissue and articular damage. Historically, medical therapy was able to slow, but not prevent, erosion and joint destruction, resulting in the frequent need for orthopedic procedures to maintain function and minimize pain. However, the widespread use of disease-modifying anti-rheumatic drugs (DMARDs) and biologic therapy over the last twenty years has resulted in a dramatic decrease in the incidence of musculoskeletal damage and impairment among these patients. This review will discuss changing patterns of orthopedic surgery among patients with rheumatic diseases, focusing on rheumatoid arthritis and systemic lupus erythematosus.

摘要

风湿性疾病是一种多系统疾病,主要影响肌肉骨骼系统,导致软组织和关节损伤。历史上,医学治疗能够减缓,但不能预防侵蚀和关节破坏,导致经常需要进行矫形手术以维持功能和减轻疼痛。然而,在过去二十年中,疾病修饰抗风湿药物(DMARDs)和生物疗法的广泛应用导致这些患者的肌肉骨骼损伤和功能障碍的发生率显著下降。本文将讨论风湿性疾病患者矫形手术模式的变化,重点讨论类风湿关节炎和系统性红斑狼疮。

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