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体细胞克隆荷斯坦奶牛后代产奶量的临床研究报告

Clinical study report on milk production in the offspring of a somatic cell cloned Holstein cow.

作者信息

Takahashi Masahiro, Tsuchiya Hideki, Hamano Seizo, Inaba Toshio, Kawate Noritoshi, Tamada Hiromichi

机构信息

Department of Advanced Pathobiology, Graduate School of Life and Environmental Sciences, Osaka Prefecture University, Osaka 598-8531, Japan.

出版信息

J Reprod Dev. 2013 Dec 17;59(6):595-8. doi: 10.1262/jrd.2013-025. Epub 2013 Aug 17.

DOI:10.1262/jrd.2013-025
PMID:23955271
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3934143/
Abstract

This study examined two female offspring of a somatic cell cloned Holstein cow that had reproduction problems and milk production performance issues. The two offspring heifers, which showed healthy appearances and normal reproductive characteristics, calved on two separate occasions. The mean milk yields of the heifers in the first lactation period were 9,037 kg and 7,228 kg. The relative mean milk yields of these cows were 111.2% and 88.9%, respectively, when compared with that of the control group. No particular clinical abnormalities were revealed in milk yields and milk composition rate [e.g., fat, protein and solids-not-fat (SNF)], and reproductive characteristics of the offspring of the somatic cell cloned Holstein cow suggested that the cloned offspring had normal milk production.

摘要

本研究对一头存在繁殖问题和产奶性能问题的体细胞克隆荷斯坦奶牛的两头雌性后代进行了检测。这两头后代小母牛外表健康,具有正常的生殖特征,分别在两个不同的时间产犊。在第一个泌乳期,小母牛的平均产奶量分别为9037千克和7228千克。与对照组相比,这些奶牛的相对平均产奶量分别为111.2%和88.9%。体细胞克隆荷斯坦奶牛后代的产奶量、乳成分率(如脂肪、蛋白质和非脂固体)以及生殖特征均未发现特别的临床异常,这表明克隆后代具有正常的产奶能力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca68/3934143/a2172e780fb6/jrd-59-595-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca68/3934143/45520737e74b/jrd-59-595-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca68/3934143/a2172e780fb6/jrd-59-595-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca68/3934143/45520737e74b/jrd-59-595-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca68/3934143/a2172e780fb6/jrd-59-595-g002.jpg

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本文引用的文献

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Non-genomic transgenerational inheritance of disease risk.疾病风险的非基因组跨代遗传
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Reproductive characteristics of cloned heifers derived from adult somatic cells.源自成年体细胞的克隆小母牛的繁殖特性。
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Cloned cattle can be healthy and normal.
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