巴西巴伊亚州某医疗中心皮肤淋巴瘤分析。

Analysis of cutaneous lymphomas in a medical center in Bahia, Brazil.

机构信息

Department of Pathology, Hospital Universitário Prof Edgard Santos, Federal University of Bahia, Brazil.

出版信息

Am J Clin Pathol. 2013 Sep;140(3):348-54. doi: 10.1309/AJCPL52QGQPZWFHE.

DOI:10.1309/AJCPL52QGQPZWFHE

PMID:23955453

Abstract

OBJECTIVES

To evaluate the frequency of the different types of cutaneous lymphoma (CL) in 1 university hospital in Brazil and compare this frequency with those observed in other countries.

METHODS

After review, 72 (84.7%) cases of primary cutaneous T-cell lymphoma (CTCL) and 13 (15.3%) cases of primary cutaneous B-cell lymphoma (CBCL) were included.

RESULTS

Of the CTCLs, 40.3% were mycosis fungoides (MF); 26.4% were adult T-cell leukemias/lymphomas (ATLs); 23.6% were peripheral T-cell lymphomas, unspecified; and 8.3% were anaplastic large cell lymphomas. Of the MF cases, 17.2% progressed to transformed MF. Five-year survival for primary human T-cell lymphotropic virus type 1-negative CTCL, ATL, and CBCL was 64.0%, 42.1%, and 62.5%, respectively. MF and ATL were the most frequent primary CTCLs.

CONCLUSIONS

The frequencies observed here are close to those observed in Peru but different from those of European countries. Unfortunately, the World Health Organization/European Organization of Research and Treatment of Cancer classification does not include primary cutaneous ATL.

摘要

目的

评估巴西 1 家大学附属医院中不同类型皮肤淋巴瘤（CL）的发病频率，并将其与其他国家的观察结果进行比较。

方法

经回顾性分析，共纳入 72 例原发性皮肤 T 细胞淋巴瘤（CTCL）和 13 例原发性皮肤 B 细胞淋巴瘤（CBCL）病例。

结果

在 CTCL 中，蕈样真菌病（MF）占 40.3%；成人 T 细胞白血病/淋巴瘤（ATL）占 26.4%；外周 T 细胞淋巴瘤，未特指占 23.6%；间变大细胞淋巴瘤占 8.3%。MF 病例中有 17.2%进展为转化型 MF。原发性人 T 细胞嗜淋巴细胞病毒 1 阴性 CTCL、ATL 和 CBCL 的 5 年生存率分别为 64.0%、42.1%和 62.5%。MF 和 ATL 是最常见的原发性 CTCL。