Bor Renáta, Fábián Anna, Farkas Klaudia, Bálint Anita, Tiszlavicz László, Wittmann Tibor, Nagy Ferenc, Molnár Tamás, Szepes Zoltán
Szegedi Tudományegyetem, Általános Orvostudományi Kar I. Belgyógyászati Klinika Szeged Korányi fasor 8-10. 6720.
Orv Hetil. 2013 Aug 25;154(34):1337-44. doi: 10.1556/OH.2013.29686.
The exact extent of rectal cancer and regional lymph node involvement are essential for providing the optimal treatment.
The aim of the authors was to evaluate the diagnostic accuracy of endoscopic ultrasonography in routine clinical staging of rectal cancer.
Outcomes of endoscopic ultrasonography performed between 2006 and 2012 for rectal cancer staging were retrospectively analyzed. The correlation between the endoscopic and pathological stages was evaluated.
In patients without neoadjuvant chemotherapy the sensitivity (75% and 73%) and specificity (74% and 80%) of endoscopic ultrasonography for differentiating T1 and T2 stages (respectively) were high, however, it was significantly decreased in differentiation of T3 stage (58%). A weak association was found in different N stages (45-62%). The diagnostic accuracy of endoscopic ultrasound was reduced significantly after the oncological treatment due to the overevaluation (27%) of the findings. After a relatively short learning curve (30 examinations) high correlation was detected between pT and uT stages.
Endoscopic ultrasonography provides great help in staging early rectal cancers. Due to the lower sensitivity in patients receiving neoadjuvant therapy, it is not a useful tool after down-staging.
直肠癌的确切范围及区域淋巴结受累情况对于提供最佳治疗至关重要。
作者旨在评估内镜超声在直肠癌常规临床分期中的诊断准确性。
回顾性分析2006年至2012年间进行的用于直肠癌分期的内镜超声检查结果。评估内镜分期与病理分期之间的相关性。
在未接受新辅助化疗的患者中,内镜超声区分T1期和T2期的敏感性(分别为75%和73%)及特异性(分别为74%和80%)较高,然而,区分T3期时敏感性显著降低(58%)。在不同N分期中发现弱相关性(45%-62%)。由于对检查结果的过度评估(27%),肿瘤治疗后内镜超声的诊断准确性显著降低。经过相对较短的学习曲线(30次检查)后,检测到pT期和uT期之间有高度相关性。
内镜超声在早期直肠癌分期中提供了很大帮助。由于在接受新辅助治疗的患者中敏感性较低,在肿瘤降期后它不是一个有用的工具。