Suppr超能文献

Toward the Ideal Synthesis and Transformative Therapies: The Roles of Step Economy and Function Oriented Synthesis.

作者信息

Wender Paul A

机构信息

Department of Chemistry, Department of Chemical and Systems Biology, Stanford University, Stanford CA 94305-5080 USA.

出版信息

Tetrahedron. 2013 Jun 7;69(36):7529-7550. doi: 10.1016/j.tet.2013.06.004.

Abstract
摘要

相似文献

2
Function through synthesis-informed design.
Acc Chem Res. 2015 Mar 17;48(3):752-60. doi: 10.1021/acs.accounts.5b00004. Epub 2015 Mar 5.
4
Biocatalysis - Key enabling tools from biocatalytic one-step and multi-step reactions to biocatalytic total synthesis.
N Biotechnol. 2021 Jan 25;60:113-123. doi: 10.1016/j.nbt.2020.08.006. Epub 2020 Oct 9.
5
Function-oriented synthesis, step economy, and drug design.
Acc Chem Res. 2008 Jan;41(1):40-9. doi: 10.1021/ar700155p. Epub 2007 Dec 27.
7
Transformative practice and its interactional challenges in COVID-19 telephone contact tracing in Flanders.
Front Psychol. 2023 Aug 30;14:1203897. doi: 10.3389/fpsyg.2023.1203897. eCollection 2023.
8
Toward the ideal synthesis and molecular function through synthesis-informed design.
Nat Prod Rep. 2014 Apr;31(4):433-40. doi: 10.1039/c4np00013g. Epub 2014 Mar 3.
9
Time and Pot Economy in Total Synthesis.
Acc Chem Res. 2021 Mar 16;54(6):1385-1398. doi: 10.1021/acs.accounts.0c00803. Epub 2021 Feb 22.
10
Transformative potential of conservation actions.
Biodivers Conserv. 2023 Apr 15:1-23. doi: 10.1007/s10531-023-02600-3.

引用本文的文献

1
Total Synthesis of (-)-Neocucurbol C Enabled by Pattern Recognition and MHAT Cyclization.
J Am Chem Soc. 2025 Aug 13;147(32):28589-28594. doi: 10.1021/jacs.5c08224. Epub 2025 Aug 4.
2
Privileged Chiral Photocatalysts.
Angew Chem Int Ed Engl. 2025 Sep 1;64(36):e202513320. doi: 10.1002/anie.202513320. Epub 2025 Aug 1.
3
Unifying principles for the design and evaluation of natural product-inspired compound collections.
Chem Sci. 2025 Jan 24;16(7):2961-2979. doi: 10.1039/d4sc08017c. eCollection 2025 Feb 12.
4
Palladium-Catalyzed Oxidative Allene-Allene Cross-Coupling.
J Am Chem Soc. 2025 Feb 5;147(5):4338-4348. doi: 10.1021/jacs.4c14607. Epub 2025 Jan 23.
6
Recent developments in one-pot stepwise synthesis (OPSS) of small molecules.
iScience. 2022 Aug 27;25(9):105005. doi: 10.1016/j.isci.2022.105005. eCollection 2022 Sep 16.
7
Synthesis of Tertiary Amines through Extrusive Alkylation of Carbamates.
Org Lett. 2022 Aug 26;24(33):6208-6212. doi: 10.1021/acs.orglett.2c02516. Epub 2022 Aug 16.
8
Mechanistic Insights on the Selectivity of the Tandem Heck-Ring-Opening of Cyclopropyldiol Derivatives.
JACS Au. 2022 Mar 5;2(3):687-696. doi: 10.1021/jacsau.1c00547. eCollection 2022 Mar 28.
9
Limonoids From the Genus (Meliaceae): Phytochemistry, Synthesis, Bioactivities, Pharmacokinetics, and Toxicology.
Front Pharmacol. 2022 Jan 24;12:795565. doi: 10.3389/fphar.2021.795565. eCollection 2021.
10
Late-Stage Diversification: A Motivating Force in Organic Synthesis.
J Am Chem Soc. 2021 Oct 20;143(41):16890-16901. doi: 10.1021/jacs.1c08920. Epub 2021 Oct 6.

本文引用的文献

5
Sustainable practices in medicinal chemistry: current state and future directions.
J Med Chem. 2013 Aug 8;56(15):6007-21. doi: 10.1021/jm400250p. Epub 2013 May 9.
7
Substrate-initiated synthesis of cell-penetrating poly(disulfide)s.
J Am Chem Soc. 2013 Feb 13;135(6):2088-2091. doi: 10.1021/ja311961k. Epub 2013 Feb 4.
8
Ni-catalyzed [4+3+2] cycloaddition of ethyl cyclopropylideneacetate and dienynes: scope and mechanistic insights.
Chemistry. 2013 Mar 4;19(10):3415-25. doi: 10.1002/chem.201204087. Epub 2013 Jan 25.
9
Stereoselective multiple bond-forming transformations (MBFTs): the power of 1,2- and 1,3-dicarbonyl compounds.
Chemistry. 2013 Feb 11;19(7):2218-31. doi: 10.1002/chem.201204018. Epub 2013 Jan 22.
10
[5 + 2] cycloaddition reactions in organic and natural product synthesis.
Chem Rev. 2013 Mar 13;113(3):2244-66. doi: 10.1021/cr300087g. Epub 2012 Nov 15.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验