运动功能恶化的儿科患者皮质脊髓束的退行性改变：一项扩散张量纤维束成像研究。
Degenerative changes of the corticospinal tract in pediatric patients showing deteriorated motor function: A diffusion tensor tractography study.
作者信息
Chang Min Cheol, Jang Sung Ho, Seo Jeong Pyo, Lee Eusil, Kim Saeyoon, Won Yu Hui, Son Su Min
机构信息
a Department of Physical Medicine and Rehabilitation , College of Medicine, Yeungnam University , Taegu , Republic of Korea .
b Department of Pediatrics , College of Medicine, Yeungnam University , Taegu , Republic of Korea , and.
出版信息
Dev Neurorehabil. 2015;18(5):290-5. doi: 10.3109/17518423.2013.821538. Epub 2013 Aug 19.
OBJECTIVE
We attempted to demonstrate the corresponding degenerative changes of the affected corticospinal tract (CST) in pediatric patients with deteriorated motor function using diffusion tensor tractography (DTT).
METHODS
We recruited three pediatric patients (corrected age: 2, 6 and 47 months, respectively) who showed impaired motor function.
RESULTS
DTT in each patient showed interruption of the CSTs of the hemisphere contralateral to the side of motor impairment. Despite motor impairment and abnormal DTT findings, none of the three patients received rehabilitative therapy. The patients (corrected age: 9, 53 and 59 months, respectively) and their parents visited our clinic again due to deterioration of motor functions. Follow-up DTT of all evaluated patients showed significant degenerative changes in the affected CSTs in accordance with the aggravation of motor impairment.
CONCLUSION
We presented degenerative changes of the affected CSTs in pediatric patients according to the deterioration of motor function.
目的
我们试图利用弥散张量纤维束成像（DTT）来证明运动功能恶化的儿科患者中受影响的皮质脊髓束（CST）的相应退行性变化。
方法
我们招募了三名运动功能受损的儿科患者（校正年龄分别为2、6和47个月）。
结果
每位患者的DTT显示运动障碍侧对侧半球的CST中断。尽管存在运动障碍和异常的DTT结果，但这三名患者均未接受康复治疗。这些患者（校正年龄分别为9、53和59个月）及其父母因运动功能恶化再次就诊于我们的诊所。所有评估患者的随访DTT显示，随着运动障碍的加重，受影响的CST出现明显的退行性变化。
结论
我们展示了儿科患者中受影响的CSTs随运动功能恶化而出现的退行性变化。
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