Department of Orthopaedics, Medical University of Vienna, Vienna, Austria.
Department of Medicine I, Clinical Division of Haematology and Haemostaseology, Medical University of Vienna, Vienna, Austria.
J Arthroplasty. 2014 Apr;29(4):749-52. doi: 10.1016/j.arth.2013.07.014. Epub 2013 Aug 17.
The clinical histories of 45 consecutively performed TKAs in 32 patients with hereditary bleeding disorders were reviewed retrospectively. The mean follow up was 88.7 (range, 24-232) months. The cumulative probability of infection free-survival was 87.8% after 180 months. When removal of component was defined as endpoint, the survival probability was 86.4% after 180 months. In regression analysis no significant independent risk factors for infection or aseptic loosening were identified. The HSS score improved significantly from 45 to 85 points. Hemophilic patients can be considered to be at high risk for prosthetic failure, our study has demonstrated favorable functional results of total knee arthroplasty in hemophilic patients.
回顾性分析了 32 例遗传性出血性疾病患者连续进行的 45 例 TKA 的临床病史。平均随访 88.7（范围，24-232）个月。180 个月时，无感染生存的累积概率为 87.8%。当以移除部件为终点时，180 个月后的生存率为 86.4%。在回归分析中，未发现感染或无菌性松动的显著独立危险因素。HSS 评分从 45 分显著提高到 85 分。血友病患者被认为是假体失败的高风险人群，但我们的研究表明，血友病患者的全膝关节置换术具有良好的功能结果。
