• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

[抗结核药物与三羧酸循环代谢产物在实验性结核病中的联合应用]

[Combined use of antitubercular drugs and metabolites of the tricarboxylic acid cycle in experimental tuberculosis].

作者信息

Sokirko T A, Maliuk V I, Klimenko M T, Suslov E I

出版信息

Probl Tuberk. 1990(4):20-3.

PMID:2395844
Abstract

The efficacy of a combined use of isoniazid together with polyzid prolonged tuberculostatic and tricarboxylic acid cycle metabolites was experimentally studied in guinea pigs. Mortality rates, pathomorphologic test data and the extent of tuberculous affection in the animals confirm a fairly high efficacy of prolonged polyzid in combination with succinate and malate as pathogenetic drugs.

摘要

在豚鼠身上通过实验研究了异烟肼与多齐特联合使用对延长抗结核作用及三羧酸循环代谢产物的效果。动物的死亡率、病理形态学检测数据以及结核感染程度证实,多齐特与琥珀酸盐和苹果酸盐联合作为病因性药物具有相当高的疗效。

相似文献

1
[Combined use of antitubercular drugs and metabolites of the tricarboxylic acid cycle in experimental tuberculosis].[抗结核药物与三羧酸循环代谢产物在实验性结核病中的联合应用]
Probl Tuberk. 1990(4):20-3.
2
[Effect of experimental use of antitubercular preparations and various pathogenetic drugs on the immunological reactions of the body].[抗结核制剂及各种病因治疗药物的实验性应用对机体免疫反应的影响]
Probl Tuberk. 1988(4):65-8.
3
[An experimental study of the chemotherapeutic efficacy of flurenizid, a new antitubercular pharmaceutical].
Probl Tuberk. 1990(6):3-7.
4
[Effect of tuberculostatic agents and sodium succinate on the functional state of liver mitochondria in tuberculosis].
Vopr Med Khim. 1987 Jul-Aug;33(4):83-6.
5
[Express intravenous administration of a complex of antituberculosis preparations in the treatment of destructive pulmonary tuberculosis].[静脉快速滴注抗结核制剂复合物治疗毁损型肺结核]
Probl Tuberk. 1977 Jul(7):35-9.
6
[Experimental study of therapeutic effect of various antibacterial drug combinations].
Probl Tuberk. 1980 Jul(7):49-53.
7
[Various indicators of the immunological response of the body after inclusion of pathogenetic agents in the chemotherapy of tuberculosis].[在结核病化疗中加入致病因子后机体免疫反应的各种指标]
Probl Tuberk. 1984 Sep(9):28-30.
8
[Chemotherapy in combination with the rapid intravenous administration of isoniazid in pulmonary tuberculosis].[肺结核中化疗联合异烟肼快速静脉给药]
Probl Tuberk. 1982 Dec(12):45-8.
9
Liposome-based antitubercular drug therapy in a guinea pig model of tuberculosis.基于脂质体的抗结核药物疗法在豚鼠结核病模型中的应用
Int J Antimicrob Agents. 2004 Apr;23(4):414-5. doi: 10.1016/j.ijantimicag.2004.01.002.
10
[Isoniazid pharmacokinetics in the combined chemotherapy of tuberculosis].[异烟肼在结核病联合化疗中的药代动力学]
Probl Tuberk. 1981 Oct(10):24-8.