使用单抗原珠Luminex检测法检测抗人白细胞抗原抗体：平均荧光强度的批次间差异 - Suppr

On the detection of anti-HLA antibodies using single antigen bead Luminex assay: lot-to-lot variations in MFI.

作者信息

Friedlander Rex, Putheti Prabhakar, Diaz Elder, Menon Arvind, Ponce Blanca, Muthukumar Thangamani, Sharma Vijay K, Dadhania Darshana, Suthanthiran Manikkam

出版信息

Transplantation. 2013 Aug 27;96(4):e24-6. doi: 10.1097/TP.0b013e31829c2481.

DOI:10.1097/TP.0b013e31829c2481

PMID:23958886

Abstract

摘要

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On the detection of anti-HLA antibodies using single antigen bead Luminex assay: lot-to-lot variations in MFI.使用单抗原珠Luminex检测法检测抗人白细胞抗原抗体：平均荧光强度的批次间差异

Transplantation. 2013 Aug 27;96(4):e24-6. doi: 10.1097/TP.0b013e31829c2481.

Clinical relevance of HLA donor-specific antibodies detected by single antigen assay in kidney transplantation.单抗原检测法检测到的 HLA 供体特异性抗体在肾移植中的临床意义。

Nephrol Dial Transplant. 2012 Mar;27(3):1231-8. doi: 10.1093/ndt/gfr429. Epub 2011 Aug 2.

Pretransplant IgG subclasses of donor-specific human leukocyte antigen antibodies and development of antibody-mediated rejection.移植前供体特异性人类白细胞抗原抗体的 IgG 亚类与抗体介导的排斥反应的发生。

Transplantation. 2011 Jul 15;92(1):41-7. doi: 10.1097/TP.0b013e31821cdf0d.

Clinical relevance of anti-HLA donor-specific antibodies detected by Luminex assay in the development of rejection after renal transplantation.Luminex 检测法检测到的抗 HLA 供体特异性抗体在肾移植后排斥反应发展中的临床相关性。

Transplantation. 2012 Aug 27;94(4):338-44. doi: 10.1097/TP.0b013e31825ace2c.

Reappraisal of HLA antibody analysis and crossmatching in kidney transplantation.肾移植中HLA抗体分析与交叉配型的重新评估

Clin Transpl. 2007:219-26.

Virtual crossmatch by identification of donor-specific anti-human leukocyte antigen antibodies by solid-phase immunoassay: a 30-month analysis in living donor kidney transplantation.固相免疫分析法鉴定供者特异性抗人类白细胞抗原抗体的虚拟交叉配型：活体供肾移植 30 个月分析。

Hum Immunol. 2010 Mar;71(3):268-73. doi: 10.1016/j.humimm.2010.01.003. Epub 2010 Jan 25.

Low median fluorescence intensity could be a nonsafety concept of immunologic risk evaluation in patients with shared molecular eplets in kidney transplantation.在肾移植中，共享分子表位的患者中低中位荧光强度可能是非免疫风险评估的安全概念。

Hum Immunol. 2012 May;73(5):522-5. doi: 10.1016/j.humimm.2012.02.020. Epub 2012 Mar 6.

Clinical and anti-HLA antibody profile of nine renal transplant recipients with failed grafts: donor-specific and non-donor-specific antibody development.9例移植肾失功的肾移植受者的临床及抗人白细胞抗原抗体谱：供者特异性和非供者特异性抗体的产生情况

Clin Transpl. 2006:241-53.

Pre-formed donor-specific alloantibodies (DSA) detected only by luminex technology using HLA-coated microspheres and causing acute humoral rejection and kidney graft dysfunction.仅通过使用包被 HLA 的微球的 Luminex 技术检测到的预先形成的供者特异性同种异体抗体（DSA），可导致急性体液排斥反应和肾移植功能障碍。

Clin Transpl. 2006:379-83.

Prevalence and significance of anti-HLA and donor-specific antibodies long-term after renal transplantation.肾移植术后长期抗人白细胞抗原及供者特异性抗体的发生率与意义

Transpl Int. 2005 May;18(5):532-40. doi: 10.1111/j.1432-2277.2005.00085.x.

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Principles of Virtual Crossmatch Testing for Kidney Transplantation.肾移植虚拟交叉配型检测原则

Kidney Int Rep. 2022 Mar 15;7(6):1179-1188. doi: 10.1016/j.ekir.2022.03.006. eCollection 2022 Jun.

Defining the structural basis for human leukocyte antigen reactivity in clinical transplantation.定义临床移植中人类白细胞抗原反应的结构基础。

Sci Rep. 2020 Oct 27;10(1):18397. doi: 10.1038/s41598-020-75355-4.

Human Leucocyte Antigen Sensitisation and Its Impact on Transfusion Practice.人类白细胞抗原致敏及其对输血实践的影响。

Transfus Med Hemother. 2019 Oct;46(5):356-369. doi: 10.1159/000502158. Epub 2019 Aug 29.

Towards uniformity in the definition of acceptable mismatches for highly sensitized patients.实现高度致敏患者可接受错配定义的一致性。

HLA. 2019 Aug;94(2):147-153. doi: 10.1111/tan.13607. Epub 2019 Jun 19.

Understanding solid-phase HLA antibody assays and the value of MFI.了解固相 HLA 抗体检测及平均荧光强度（MFI）的价值。

Hum Immunol. 2017 Jul-Aug;78(7-8):471-480. doi: 10.1016/j.humimm.2017.05.007. Epub 2017 May 30.

Immunological risk assessment and human leukocyte antigen antibody testing in kidney transplantation.肾移植中的免疫风险评估与人类白细胞抗原抗体检测

Indian J Nephrol. 2016 Mar-Apr;26(2):80-5. doi: 10.4103/0971-4065.167275.

The Influence of Immunosuppressive Agents on the Risk of De Novo Donor-Specific HLA Antibody Production in Solid Organ Transplant Recipients.免疫抑制剂对实体器官移植受者产生新发供者特异性HLA抗体风险的影响。

Transplantation. 2016 Jan;100(1):39-53. doi: 10.1097/TP.0000000000000869.

Development and validation of a prognostic index for allograft outcome in kidney recipients with transplant glomerulopathy.移植肾小球病肾移植受者同种异体移植物预后指数的开发与验证

Kidney Int. 2016 Feb;89(2):450-8. doi: 10.1038/ki.2015.288.

Utility of HLA Antibody Testing in Kidney Transplantation.人类白细胞抗原抗体检测在肾移植中的应用

J Am Soc Nephrol. 2015 Jul;26(7):1489-502. doi: 10.1681/ASN.2014080837. Epub 2015 Mar 24.

Characteristics of Circulating Donor Human Leukocyte Antigen-specific Immunoglobulin G Antibodies Predictive of Acute Antibody-mediated Rejection and Kidney Allograft Failure.循环供体人类白细胞抗原特异性免疫球蛋白G抗体的特征对急性抗体介导的排斥反应和肾移植失败具有预测作用。

Transplantation. 2015 Jun;99(6):1156-64. doi: 10.1097/TP.0000000000000511.

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On the detection of anti-HLA antibodies using single antigen bead Luminex assay: lot-to-lot variations in MFI.

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