School of Psychology, University of Nottingham, UK.
Brain Cogn. 2013 Oct;83(1):132-41. doi: 10.1016/j.bandc.2013.07.010. Epub 2013 Aug 17.
The cognitive sequelae of hydrocephalus have mostly been explored with standardised clinical tasks. The aim of the present research was determine whether impairments on these abstract tasks extend to everyday spatial and navigational behaviour. Patients with hydrocephalus, but without spina bifida, were compared to a control group on tests of searching behaviour, landmark memory, route learning, and path integration. Participants with hydrocephalus displayed reduced sensitivity to spatial cueing, less accurate route-learning, and significantly less accurate spatial updating. These data represent an important empirical demonstration of spatial navigational impairments due to hydrocephalus outside of the context of spina bifida. We discuss some of the cognitive, neural, and individual differences factors that might contribute to this particular pattern of impairments.
脑积水的认知后遗症主要通过标准化的临床任务来探索。本研究的目的是确定这些抽象任务的损伤是否会延伸到日常的空间和导航行为。将没有脊柱裂的脑积水患者与对照组进行搜索行为、地标记忆、路线学习和路径整合测试。脑积水患者对空间提示的敏感性降低，路线学习的准确性降低，空间更新的准确性显著降低。这些数据代表了在没有脊柱裂的情况下，脑积水导致空间导航障碍的重要实证证明。我们讨论了一些可能导致这种特殊损伤模式的认知、神经和个体差异因素。
