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人类红细胞酸性磷酸酶新变体EB的报告与特性描述。

Report and characterization of a new variant, EB, of human red cell acid phosphatase.

作者信息

Sorensen S A

出版信息

Am J Hum Genet. 1975 Jan;27(1):100-9.

Abstract

A new variant phenotype of human red cell acid phosphatase, designated EB, was discovered in a male during a survey of blood donors from Copenhagen, Denmark. Electrophoretically, the variant revealed the two isozymes corresponding to the B type as well as two fast moving anodic isozymes. The enzyme activity and thermostability were found to be higher than in any earlier reported type. Isoelectric focusing of the variant type indicated that the isoelectric point of the variant enzyme is lower than in the common types.

摘要

在对丹麦哥本哈根献血者的一项调查中,一名男性体内发现了一种新的人类红细胞酸性磷酸酶变异表型,命名为EB。电泳显示,该变异体呈现出与B型相对应的两种同工酶以及两种快速移动的阳极同工酶。研究发现,该酶的活性和热稳定性高于此前报道的任何类型。对该变异类型进行等电聚焦分析表明,变异酶的等电点低于常见类型。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c375/1762776/ecbe8ed7337b/ajhg00434-0105-a.jpg

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