桥粒芯糖蛋白：毛发视角
Desmogleins: hair perspective.
作者信息
Nigam Pramod Kumar
机构信息
Department of Dermatology and STD, Pt. J.N.M. Medical College, Raipur, Chhattisgarh, India.
出版信息
Int J Trichology. 2013 Jan;5(1):2-5. doi: 10.4103/0974-7753.114695.
Abstract
Desmogleins (Dsgs) are calcium-dependent, transmembrane glycoproteins belonging to the desmosomal cadherin superfamily, which play significant roles in selective calcium ions (Ca(2+)) dependent adhesion interactions between cell surfaces. Four subtypes of Dsg have been identified. Recent observations show the distribution of Dsgs can correlate with specific types of keratinization, anchorage of the hair, and hypotrichosis.
摘要
桥粒芯糖蛋白（Dsgs）是一种依赖钙的跨膜糖蛋白，属于桥粒钙黏蛋白超家族，在细胞表面之间选择性钙离子（Ca(2+)）依赖的黏附相互作用中发挥重要作用。已鉴定出四种Dsgs亚型。最近的观察结果表明，Dsgs的分布可能与特定类型的角化、毛发固定和毛发稀少有关。
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