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表现为库欣病的垂体嗜酸性细胞瘤。

Pituitary oncocytoma presenting as Cushing's disease.

作者信息

Garg M K, Bharwaj Reena, Pathak H C, Kharb Sandeep, Gundgurthi Abhay, Pandit Aditi, Brar K S

机构信息

Department of Endocrinology, Army Hospital (Research & Referral), Delhi Cantt-10, India.

出版信息

Indian J Endocrinol Metab. 2013 Jul;17(4):759-62. doi: 10.4103/2230-8210.113778.

Abstract

A 19-year-old girl presented with classical features of Cushing's syndrome. Endocrinal evaluation was consistent with pituitary source of ACTH; but imaging showed normal pituitary. Bilateral inferior petrosal sinus sampling confirmed the diagnosis. A successful remission was achieved after adenomectomy by transphenoidal route. Histopathological examination was consistent with pituitary oncocytoma and immunohistochemistry was positive for synaptophysin, chromogranin, neuron specific enolase, S-100, ACTH, prolactin, and GH.

摘要

一名19岁女孩表现出库欣综合征的典型特征。内分泌评估结果与促肾上腺皮质激素(ACTH)的垂体来源一致;但影像学检查显示垂体正常。双侧岩下窦采血确诊了该疾病。经蝶窦途径行腺瘤切除术后实现了成功缓解。组织病理学检查结果与垂体嗜酸性细胞瘤一致,免疫组化显示突触素、嗜铬粒蛋白、神经元特异性烯醇化酶、S-100、ACTH、催乳素和生长激素均呈阳性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2b0/3743387/3d7bf10dbbe6/IJEM-17-759-g001.jpg

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