Skorobogatyĭ A M
Vrach Delo. 1990 May(5):92-4.
Data are summarized on the interaction of drugs when several of them are used simultaneously. A scheme is presented based on the principle of location of the drug in the body, correspondence of the preplanned effect and actual efficacy, pharmaceutic, pharmacokinetic, pharmacodynamic phases. These findings allow to objectivize and plan rational, effective and safe treatment. Evaluation of interaction of drugs used simultaneously permits to organize a qualitatively optimal and an economically advantageous variant of pharmacotherapy.
总结了几种药物同时使用时药物相互作用的数据。根据药物在体内的定位原则、预先计划的效果与实际疗效的对应关系、药剂学、药代动力学、药效学阶段，提出了一种方案。这些发现有助于客观化并规划合理、有效和安全的治疗。对同时使用的药物相互作用进行评估，有助于组织定性最优且经济有利的药物治疗方案。
