Draganov V, Orbetsov M, Pavlov V
Vutr Boles. 1990;29(1):30-5.
48 patients, 40 men (mean age 57.4 years) and 8 women (mean age 56.7 years) with stable arterial pressure--II B and III stage according to A. L. Miasnikov's classification, were treated and followed up dynamically in the course of 8 years. The treatment with diuretics, beta-blockers and reserpin has led to a permanent and satisfactory regulation of arterial pressure in most of the patients. Only in 10.4% of the patients the therapeutic results were not satisfactory. In spite of the normalization of the arterial pressure the number of patients with various forms of ischemic heart disease is high--79.2%. The risk factors and their combinations play an important role for this condition (diabetes mellitus, gout, obesity, lipid metabolism changes, etc.). These data imply a new assessment of the drugs used in the treatment of arterial hypertension.
48例患者,40名男性(平均年龄57.4岁)和8名女性(平均年龄56.7岁),动脉血压稳定,根据A.L.米亚斯尼科夫分类为II B期和III期,在8年期间接受治疗并进行动态随访。使用利尿剂、β受体阻滞剂和利血平治疗使大多数患者的动脉血压得到持久且满意的控制。仅10.4%的患者治疗效果不满意。尽管动脉血压已恢复正常,但患有各种形式缺血性心脏病的患者数量仍很高——79.2%。危险因素及其组合对这种情况起重要作用(糖尿病、痛风、肥胖、脂质代谢改变等)。这些数据意味着对用于治疗动脉高血压的药物需要重新评估。