Mahasup Namfon, Sritipsukho Paskorn, Lekskulchai Raweewan, Hansakunachai Tippawan
Postgraduate Studies Program, Faculty of Medicine, Thammasat University, Pathumthani, Thailand.
J Med Assoc Thai. 2012 Jan;95 Suppl 1:S166-72.
The authors aimed to compare the motor function measured by Gross Motor Function Measure (GMFM-66) between mirror neurons stimulation based VCD program at home and conventional physical therapy in children with cerebral palsy for two months.
A randomized controlled trial was performed with thirty children with spastic diplegia aged 2-10 years in Thammasat university hospital and Rajanukul institue. They were randomly assigned to receive either the mirror neurons stimulation based VCD program practice at home (experimental group) or the conventional physical therapy (control group) for two months. Both groups were measured the motor function by GMFM-66 at entry, the first month and the end of the second month. Analysis of covariance was used to compare mean changes of GMFM-66 scores between both groups at the second month after adjusted for the baseline level.
A total of 30 children with cerebral palsy, aged 2.2-9.5 years (mean age 5.9 +/- 2.2 years). The mean changes of the GMFM scores in experimental group were slightly higher than those in the control group of 2.1 (95% CI: -2.3, 6.5) at the second month after adjusted for the baseline level. The mean GMFM scores were significantly improved in all dimensions except lying and rolling dimension, at the first and second month when compared to the baseline level in both groups.
This pilot study demonstrated the mirror neurons stimulation based VCD program can improve motor function, at least, as much as the conventional physical therapy.
作者旨在比较针对脑瘫儿童，在家中进行基于镜像神经元刺激的视频光盘（VCD）程序治疗与传统物理治疗两个月后，通过粗大运动功能测量（GMFM - 66）所测得的运动功能。
在泰国法政大学医院和拉贾努库尔研究所，对30名年龄在2至10岁的痉挛型双瘫儿童进行了一项随机对照试验。他们被随机分配，一组在家中接受基于镜像神经元刺激的VCD程序训练（实验组），另一组接受传统物理治疗（对照组），为期两个月。两组在入组时、第一个月和第二个月末均通过GMFM - 66测量运动功能。在对基线水平进行校正后，采用协方差分析比较两组在第二个月末GMFM - 66评分的平均变化。
共有30名脑瘫儿童，年龄在2.2至9.5岁之间（平均年龄5.9±2.2岁）。在对基线水平进行校正后，实验组GMFM评分在第二个月的平均变化略高于对照组，为2.1（95%可信区间：-2.3，6.5）。与基线水平相比，两组在第一个月和第二个月时，除卧位和翻身维度外，所有维度的GMFM平均评分均有显著改善。
这项初步研究表明，基于镜像神经元刺激的VCD程序至少能与传统物理治疗一样有效地改善运动功能。
