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[儿童Vogt-小柳-原田综合征——一例报告]

[Vogt-Koyanagi-Harada syndrome in children - a case report].

作者信息

Bušányová B, Tomčíková D, Gerinec A

出版信息

Cesk Slov Oftalmol. 2013 Jun;69(2):81-6.

Abstract

Vogt-Koyanagi-Harada (VKH) syndrome is a multisystemic disease characterized by granulomatous panuveitis with exsudative retinal detachment and often associated with neurological and skin symptomatology. In the paper is presented a rare case of probably VHK syndrome in 11-year old caucasian race boy in which was found the bilateral granulomatous panuveitis with exsudative retinal detachment without other systemic symptomatology with typical clinical characteristics and course. Systemic corticosteroid therapy in a patient gradually improved the state, which was then complicated by the occurrence of juxtapapillary subretinal neovascular membrane on both eyes. The following administration of intravitreal injection anti-VEGF (bevacizumab) was modified visual acuity and reduced neovascular membrane. Key words: Vogt-Koyanagi-Harada syndrome, children, juxtapapillary choroidal neovascular membrane, anti-VEGF, bevacizumab.

摘要

伏格特-小柳-原田(VKH)综合征是一种多系统疾病,其特征为肉芽肿性全葡萄膜炎伴渗出性视网膜脱离,常伴有神经和皮肤症状。本文介绍了一名11岁白种男孩可能患有VHK综合征的罕见病例,该病例中发现双侧肉芽肿性全葡萄膜炎伴渗出性视网膜脱离,无其他全身症状,具有典型的临床特征和病程。患者接受全身糖皮质激素治疗后病情逐渐改善,但随后双眼出现视乳头旁视网膜下新生血管膜,使病情复杂化。随后给予玻璃体内注射抗VEGF(贝伐单抗)治疗,改善了视力并减少了新生血管膜。关键词:伏格特-小柳-原田综合征;儿童;视乳头旁脉络膜新生血管膜;抗VEGF;贝伐单抗

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