Department of Surgery, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.
Surg Infect (Larchmt). 2013 Aug;14(4):415-7. doi: 10.1089/sur.2012.140.
Melioidosis, a lethal infectious disease caused by Burkholderia pseudomallei, an important human pathogen in tropical regions, is notorious for its diverse clinical presentations.
We report a case of a 55-year-old woman with a history of total abdominal hysterectomy with bilateral salpingo-oophorectomy for ovarian mucinous cystadenocarcinoma five years back, who presented with complaints of chest pain, abdominal distention, and breathlessness for one week. Ultrasound-guided aspiration of the peritoneal free fluid revealed a thick gelatinous material consistent with pseudomyxoma peritonei. Cytologic analysis of the aspirate was negative for malignant cells, but bacterial culture proved positive for Burkholderia pseudomallei.
She was started on ceftazidime, and she improved symptomatically and was discharged on oral doxycycline and chloramphenicol after three weeks of intravenous antibiotic therapy.
This case is being reported to emphasize an unusual presentation of melioidosis and the significance of timely appropriate antibiotic therapy.
类鼻疽病是一种由伯克霍尔德氏菌引起的致命性传染病,该菌也是热带地区的一种重要人类病原体,其临床表现多样,因而臭名昭著。
我们报告了一例 55 岁女性病例,该患者五年前行全子宫切除术和双侧输卵管卵巢切除术,用于治疗卵巢黏液性囊腺癌,现因胸痛、腹胀和呼吸困难一周就诊。超声引导下抽吸腹腔游离液,发现符合假性黏液瘤的浓稠胶状物质。抽吸物的细胞学分析未发现恶性细胞,但细菌培养证实为伯克霍尔德氏菌。
患者开始接受头孢他啶治疗,在静脉用抗生素治疗 3 周后,患者症状改善,并出院改为口服多西环素和氯霉素。
本病例报告旨在强调类鼻疽病的一种不常见表现,以及及时适当使用抗生素治疗的重要性。