Anesthesiologists of Greater Orlando, Orlando, FL 32803, USA.
Department of Anesthesiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA; Anesthesiology Service, Clement J. Zablocki Veterans Affairs Medical Center, Milwaukee, WI 53295, USA.
J Clin Anesth. 2013 Aug;25(5):403-406. doi: 10.1016/j.jclinane.2012.11.016. Epub 2013 Aug 17.
Noonan syndrome is a relatively common genetically transmitted disorder characterized by facial, cardiac, and musculoskeletal abnormalities. The management of a 27 year old woman with Noonan syndrome at 23 weeks' gestation, presenting with premature labor, who required an emergent Cesarean section for placental abruption, is discussed. In addition to Noonan syndrome, this patient had bacterial endocarditis involving the mitral and aortic valves. The anesthetic implications of Noonan syndrome and endocarditis during pregnancy are presented.
努南综合征是一种相对常见的遗传性疾病，其特征为面部、心脏和骨骼肌肉异常。讨论了一位 27 岁的努南综合征女性患者在 23 周妊娠时出现早产，因胎盘早剥需要紧急剖宫产。除努南综合征外，该患者还患有累及二尖瓣和主动脉瓣的细菌性心内膜炎。本文介绍了努南综合征和心内膜炎在怀孕期间的麻醉影响。
