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[Circumferential resection margin in the modern treatment of rectal cancer].

作者信息

Ihnát P, Martínek L, Ihnát Rudinská L, Mitták M, Vávra P, Zonča P

机构信息

Katedra chirurgickych oboru, Lekarska fakulta, Ostavske Univerzity, Ostrava.

出版信息

Rozhl Chir. 2013 Jun;92(6):297-303.

PMID:23965313
Abstract

INTRODUCTION

In the last decades, the assessment of circumferential resection margin (CRM) has gained enormous importance in the management of patients with rectal carcinoma, not only in predicting the prognosis, but also in precise cancer staging, in multimodal treatment indications and in quality assessment of provided care.

METHODS

The authors present a review article containing CRM definition, describing the technique of CRM assessment, the effect of CRM status on the prognosis and quality of provided therapy. CRM assessment in the context of a multidisciplinary team is especially emphasised. The aspect of CRM has to be considered by the radiologist during cancer staging, the surgeon in the course of the operation, the pathologist during precise macroscopic and histopathological specimen evaluation, and the oncologist when deciding on neoadjuvant/adjuvant therapy administration.

CONCLUSION

CRM nowadays represents a fundamental aspect in modern treatment of patients with rectal carcinoma. The introduction of CRM assessment into clinical practice has lead to more precise staging, better multimodal therapy indications, more precise surgical technique (total mesorectal excision), an increased rate of sphincter-saving resections, lowered local recurrence rates and improved patient survival.

摘要

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[Circumferential resection margin in the modern treatment of rectal cancer].
Rozhl Chir. 2013 Jun;92(6):297-303.
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